摘要
自蛇毒（ＤｕｃｈｅｓｎｅａｉｎｄｉｃａＦｏｃｋ）全草中分离出６个化合物，其中，２个为新化合物，分别命名为蛇莓甙Ａ（ｄｕｃｈｅｓｉｄｅＡ）和蛇莓甙Ｂ（ｄｕｃｈｅｓｉｄｅＢ），经化学及光谱（ＵＶ，１Ｒ，１ＨＮＭＲ，１３ＣＮＭＲ，ＮＯＥＤＳ和ＭＳ）分析确定，蛇莓甙Ａ的结构为３＇－Ｏ－甲基－鞣花酸－４－Ｏ－β－Ｄ－吡喃木糖甙（Ⅰ），蛇莓甙Ｂ的结构为３＇－Ｏ－甲基－鞣花酸－４－Ｏ－α－Ｌ－呋喃阿拉伯糖甙（Ⅱ）。另外４个化合物为已知三萜类化合物：３β－羟基－乌苏烷－１２－烯－２８－羧酸（Ⅲ），２α，３β，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸（Ⅳ），２α，３β，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸－２８－Ｏ－β－Ｄ－吡喃葡萄糖甙（Ⅴ），２α，３α，１９α－三羟基－乌苏烷－１２－烯－２８－羧酸－２８－Ｏ－β－Ｄ－吡喃葡萄糖甙（Ⅵ）。其中化合物Ⅳ，Ⅴ和Ⅵ为首次从该属植物中分离得到。
Two new ellagic glycosides,named ducheside A and ducheside B,have beenisolated from Ducheside indica Focke.Their structures were established as 3'-O-methyl-ellagic acid-4-O-β-D-xylopyranoside(Ⅰ),3'-O-methyl-ellagic acid-4-O-α-L-arabinofuranoside(Ⅱ),respec-tively,on the basis of chemical method and spectral analysis.In addition,four known compoundswere isolated and identified as 3β-hydroxylurs-12-en-28-oic acid(Ⅲ),2α,3β,19α-trihydroxylurs-12-en-28-oic acid(Ⅳ),2α,3β,19α-trihydroxylurs-12-en-28-oic acid-28-O-β-D-glucopyranoside(Ⅴ),2α,3α,19α-trihydroxylurs-12-en-28-oic acid-28-O-β-D-glucopyranoside(Ⅵ).CompoundsⅣ,Ⅴ,Ⅵ were isolated for the first time from Duchesnea genus.
出处
《药学学报》
CAS
CSCD
北大核心
1996年第11期844-848,共5页
Acta Pharmaceutica Sinica
关键词
蛇莓
蛇莓甙A
蛇莓苷B
鞣花甙
三萜类
化学成分
Duchesnea indica Focke
Ducheside A
Ducheside B
Ellagic glycoside
Triterpenoids
