摘要
目的 探讨德维可皮肤保护剂和赛肤润对肝癌射波刀治疗患者肝区照射野皮肤急性放射性损伤的防护效果.方法 2016年3—11月采用方便抽样法选取100例接受射波刀治疗的肝癌患者,随机分为德维可组和塞肤润组,每组50例.放射治疗前1 d起,两组患者肝区照射野皮肤分别开始使用德维可皮肤保护剂和赛肤润.对射波刀治疗期间肝区照射野皮肤急性放射性损伤进行从治疗开始前1 d至治疗结束满2周的观察.结果 观察期内两组患者肝区照射野皮肤急性放射性损伤程度的RISRAS得分随照射累计剂量的增加而增加,差异有统计学意义（F值分别为3.780、12.325;P〈0.05）.两组间的比较在第5次及以后的评估差异有统计学意义（t值分别为5.213、12.437、16.846;P〈0.05）.结论 采取局部预防性干预措施,肝癌射波刀治疗患者肝区照射野皮肤急性放射性损伤可减轻.德维可皮肤保护剂对肝癌射波刀治疗患者肝区照射野皮肤的防护作用优于赛肤润.
Objective To explore the protective effect of DWK skin protectant and Sanyrene for prevention of acute radiation skin injury in radiation field among liver cancer patients with Cyberknife therapy. Methods A total of 100 liver cancer patients with Cyberknife therapy were selected by convenience sampling from March to November 2016. They were randomly divided into the group of DWK and the group of Sanyrene with 50 cases in each group. Skins in radiation field on hepatic region of patients in two groups used DWK skin protectant and Sanyrene respectively since one day before radiotherapy. The acute radiation skin injury of radiation field on hepatic region was observed from one day before treatment to two weeks the end of treatment during Cyberknife therapy.Results The scores of The Radiation Induced Skin Reaction Assessment Scale （RISRAS）, an instrument for assessing the degree of acute radiation skin injury of radiation field on hepatic region, of patients in two groups increased with the increasing cumulated dose of irradiation with significant differences （F=3.780, 12.325;P〈0.05）. There were statistically significant differences in evaluations at the fifth and beyond between two groups （t=5.213, 12.437, 16.846;P〈0.05）.Conclusions Intervention for local prevention can alleviate the acute radiation skin injury in radiation field on hepatic region among liver cancer patients with Cyberknife therapy. The protective effect of DWK skin protectant on skin in radiation field on hepatic region among liver cancer patients with Cyberknife therapy is better than that of Sanyrene.
出处
《中华现代护理杂志》
2017年第29期3769-3771,共3页
Chinese Journal of Modern Nursing
关键词
肝肿瘤
射波刀
放射性损伤
皮肤保护
Liver neoplasms
Cyberknife
Radiation damage
Skin protection
作者简介
通信作者：刘丽英，Email：195593665@qq．com.
