摘要
目的:分析胎儿药源性疾病与孕妇不合理用药的相关性,为避免胎儿药源性疾病的发生提供参考。方法:通过调查问卷、病历调查的方式收集临床不合理用药孕妇的用药情况、胎儿发育情况及新生儿健康状况,评价不合理用药与胎儿药源性疾病的相关性。结果:孕妇在怀孕期间服用庆大霉素、依托红霉素、利巴韦林、绒促性素、丙基硫氧嘧啶、维生素B6、维生素D、维生素C、诺氟沙星、磺胺药、吲哚美辛和乙酰水杨酸盐均能引起胎儿药源性疾病,且其与用药时间过早、时长过久和剂量过大成正相关(P<0.05)。结论:胎儿药源性疾病与孕妇的不合理用药有一定的相关性,故孕妇应在医生指导下合理用药,以确保胎儿的身体健康。
Objective： To analyze the correlation between fetus drug-induced diseases and pregnant women＇s medication irrationality, and to provide reference to avoid the occurrence of fetal drug borne diseases. Methods： The questionnaire and clinical record survey were used to collect the irrational drug usage of pregnant women, neonatal development and fetal health. Moreover, the relationship between the irrational drug usage and fetal medicine source disease was evaluated. Results： During pregnancy, taking garamycina, lauritran, ribavirin, human chorionic, procasil, vitamin B6, vitamin D, vitamin C, floxacin, sulfonamides, indomethacin and acetylsalicylic acid could cause fetal drug induced diseases, which has a positive correlation with early beginning, long time and excessive dosage medication. Conclusion： There is certain correlation between fetus drug-induced diseases and pregnant women irrational drug usage. Therefore, pregnant women should be administered under the doctor＇ reasonable guidance, so as to ensure fetus health.
出处
《抗感染药学》
2017年第6期1109-1112,共4页
Anti-infection Pharmacy
关键词
胎儿
药源性疾病
孕妇
不合理用药
相关性
fetus
drug-induced diseases
pregnant women
medication irrationality
correlation
作者简介
王富海（1978一），男，副主任药师 联系电话：13727406618 E-mail：wangfuhai1978@126．com
