摘要
目的:探讨老年恶性肿瘤患者住院时的营养状况,分析营养不良与1年内病死率之间的关系。方法:采用微型营养评定简表(mininutritional assessment-short form,MNA-SF)评估因确诊恶性肿瘤入住瑞金医院老年病科的老年患者的营养状况,同时测定患者体质量指数(body mass index,BMI)、血红蛋白、前白蛋白、白蛋白、三酰甘油、总胆固醇,跟踪随访其1年生存期。结果:124例患者纳入研究,根据MNA-SF评分,营养正常(86例)、营养不良风险(33例)和营养不良(5例)的检出率分别为69.4%、26.6%和4.0%。所有患者中,总的1年内病死率为17.7%;3组患者中,以营养不良组为最高(3/5)。校正混淆变量后,COX回归模型提示营养不良将增加老年恶性肿瘤患者1年内死亡的风险。结论:营养不良在一定程度上能够独立预测老年恶性肿瘤患者1年内的死亡风险。
Objectives： To investigate the nutritional status of elderly malignant tumor patients and to analyze the relation between malnutrition and one-year mortality. Methods： The nutritional status of elderly patients diagnosed as malignant tumor admitted in the department of gerontology, Ruijin Hospital were assessed by mininutritional assessment-short form（MNA-SF）, and body mass index（BMI）, hemoglobin, prealbumin, albumin, triglyceride and total cholesterol were measured and the patients were followed up for calculating the one-year survival. Results： One hundred and twenty four patients were included in the study. The incidence of nutrition, risky malnutrition and malnutrition was 69.4%, 26.6%and 4.0%, respectively, according to the MNA-SF. The one-year mortality was 17.7% in overall patients; and among the three groups, the one-year mortality was the highest（60%） in malnutrition group. After adjustment for confounding variables, COX regression model suggested that malnutrition can increase the risk of one-year mortality. Conclusions： Malnutrition can predict independently the risk of death of the elderly malignant tumor patients within one year.
出处
《诊断学理论与实践》
2017年第4期425-429,共5页
Journal of Diagnostics Concepts & Practice
基金
国家自然科学青年科学基金项目(81502693)
关键词
老年恶性肿瘤
营养状况
微型营养评定简表
病死率
Elderly malignant tumor
Nutritional status
Risky nutritional status
MNA-SF
Mortality
作者简介
通讯作者：曹伟新E-mail：cwx103@163．com
