摘要
目的对比观察原位再生医疗技术治疗糖尿病足的临床疗效。方法对2015年12月—2016年12月收治的56例糖尿病足患者(86处创面)采用原位再生医疗技术治疗,并将其设定为治疗组;回顾性分析2014—2015年采用美皮康治疗的50例糖尿病足患者(65处创面),并将其设定为对照组。对比观察两组患者的临床疗效。结果治疗3个月后,两组患者1级及2级创面均完全愈合,P>0.05,差异无统计学意义;3级及4级创面愈合情况对比采用x^2检验,x^2=4.11及4.29,P均<0.05,差异具有统计学意义。治疗过程中,治疗组使用抗生素抗感染者22例,对照组使用抗生素抗感染者38例,两组对比,x^2=14.5,P<0.01,差异具有统计学意义。结论原位再生医疗技术可有效促进糖尿病足溃疡创面的愈合,降低抗生素使用率,疗效显著,且操作简便,可院外自行换药治疗,患者依从性较好,值得临床推广应用。
Objective To observe the clinical effect of the in situ regenerative medical technology in the treatment of diabetic foot. Methods Fifty-six patients with diabetic foot （85 wounds） admitted between December 2015 and Decem- ber 2016 were treated with the in situ regenerative medical technology, and were set as the treatment group. Fifty patients with diabetic foot （65 wounds）, who were admitted between 2014 and 2015 and treated with Mepilex, were retrospectively analyzed and set as the control group. The clinical curative effects in the two groups were observed and compared. Results Three months after the treatment, the grade 1 and 2 wounds in the two groups were all completely healed, P 〉 0. 05 showing no statistically significant difference; the wound healing condition of grade 3 and 4 wounds was compared between the two groups withx2 test and the results showed statistically significant difference, withA2 = 4. 11 and 4. 29 respectively, both P 〈 0. 05. During the treatment, 22 patients in the treatment group used antibiotics to control infection, while in the control group, 38 patients used antibiotics for the same purpose, the comparison showed statistically significant difference, with X2 = 14. 5, P 〈 O. 01. Conclusion The in situ regenerative medieal technology in the treatment of diabetic foot can realize significant curative effects such as effectively promoting the healing of diabetic foot ulcer wounds and reducing the use of an- tibiotics. In addition, the technology is easy and convenient to operate that patients can use it at home by themselves,enjoying better patients＇ compliance.
出处
《中国烧伤创疡杂志》
2017年第4期262-266,共5页
The Chinese Journal of Burns Wounds & Surface Ulcers
关键词
原位再生医疗技术
湿润烧伤膏
创疡贴
糖尿病足
疗效
The in situ regenerative medical technology
MEBO
MEBO Wound and Ulcer Dressing
Diabeticfoot
Curative effect
作者简介
通讯作者：刘井双，E-mail：286853281@qq．com
