摘要
目的观察择期宫颈环扎术联合间苯三酚治疗宫颈机能不全的临床疗效,探讨其临床应用价值。方法选择收治的87例宫颈机能不全患者作为研究对象,随机将其分为两组,观察组(n=45)行择期宫颈环扎术联合间苯三酚治疗,对照组(n=42)给予期待疗法(嘱卧床休息,口服地屈孕酮)。随访两组患者的妊娠结局。结果观察组41例获得活婴,占91.11%,对照组32例获得活婴,占76.19%,组间比较差异有统计学意义(P<0.05);观察组的平均分娩孕周(35.26±2.54周)长于对照组(32.08±2.63周),新生儿出生体重(3 320.52±392.52 g)高于对照组(2 680.56±453.20 g),组间比较差异均有统计学意义(P<0.05);观察组的早产率(17.14%)低于对照组(40.63%),差异有显著性(P<0.05)。结论择期宫颈环扎术联合间苯三酚治疗宫颈机能不全可以显著地延长患者的孕周,并降低其早产风险、改善新生儿预后,在改善妊娠结局方面具有很高的临床应用价值。
Objective To observe 出 e efficacy of selective cervical cerclage joint phloroglucinol in treatment of cervical to explore its value for clinical application. Methods A total of 87 patients with cervical insufficiency in this hospital were selected for this study, they were randomly divided into two groups, patients in observation group （ n = 45 ） were applied with cervical cerclage joint phloroglucinol for treatment, and patients in control group （n = 42） were given with expectant treatment （lying on the bed, and oral administration of dydrogestro- ne） , the outcome of pregnancy in patients of these 2 groups had been followed - up. Results 41 cases in observation group received live birth, accounted for 91.11% , and 32 cases in control group received live birth, accounted for 76.19% , there was significant difference between these two groups （ P 〈0.05）. The average gestational age （35.26 ±2.54 weeks） in observation group was longer than that of control group （32. 08 土 2. 63 weeks） , and the neonatal birth weight （3 320. 52 ± 392. 52 g） was higher than that of control group （2 680. 56 ± 453.20 g） , and the differ-ence between these two groups was significant （ P 〈0. 0 5） . The premature rate （17. 14% ） of observation group was lower than that of control group （40.63%） , and the difference was significant （ P 〈 0 .0 5 ） . Conclusion Selective cervical cerclage joint with phloroglucinol in treatment of cervical insufficiency can significantly prolong the gestational age, and reduce their risk of premature birth, and improve the prognosis of neo-nates ,this is the way to improve the outcome of pregnancy, and it has high significance for clinical application.
出处
《临床和实验医学杂志》
2017年第15期1539-1542,共4页
Journal of Clinical and Experimental Medicine
关键词
宫颈机能不全
宫颈环扎术
择期手术
间苯三酚
妊娠结局
Cervical insufficiency
Cervical cerclage
Undergoing selective surgery
Phloroglucinol
Pregnancy outcomes
作者简介
通讯作者：刘丹萍,E-mail：zengyouling_1976@msarticleonline.cn
