摘要
乳腺浸润性微乳头状癌(invasive micropapillary carcinoma,IMPC)曾被定义为乳腺浸润性导管癌的一种亚型,2012年《世界卫生组织乳腺肿瘤分类》将其独立列为一种特殊亚型的乳腺癌,其在病理上独特的表现、临床上极高的淋巴结转移率以及较差的预后使得其与单纯型浸润性导管癌比较,均有其特异性。近年来,随着对乳腺浸润性微乳头状癌研究的深入,越来越多与其特性相关的分子标志物被医学界瞩目,为IMPC的特异性治疗提供了证据和目标。
Invasive Micropapillary Carcinoma of the Breast(IMPC of the breast)was ever defined as one of the subtypes of invasive ductal carcinoma of the breast.Then in 2012,IMPC of the breast was classified as an isolated subtype of breast cancer by WHO Classification of Tumors of the Breast.Compared with pure invasive ductal carcinoma,IMPC of the breast is with specificity because of its unique pathological features,higher incidence of lymphatic metastasis and poorer prognosis.In recent years,increased amount of molecular markers were discovered as the intensive study of IMPC of the breast,which afford new evidence and targets to its specific treatment.
出处
《临床外科杂志》
2017年第4期316-318,共3页
Journal of Clinical Surgery
关键词
微乳头状癌
病理特征
临床表现
分子标志物
诊治
micropapillary carcinoma
pathological features
clinical manifestation
molecular markers
diagnosis and treatment
作者简介
通信作者:杨学伟,Email:yangxw11855@163.com