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肺癌早期诊断方法及临床意义 被引量:42

The Methods and Clinical Significance of Early Diagnosis of Lung Cancer
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摘要 肺癌是全球发病率及死亡率最高的恶性肿瘤,五年生存率约为15.6%,其原因与缺乏筛查及肺癌患者在诊断时约75%已属晚期有关。因此,肺癌的早期诊断是目前肺癌领域面临的主要挑战之一。而肺癌筛查是发现早期肺癌的重要手段,对筛查发现的肺部结节进行科学的评估及处理,深入研究高特异性、高敏感性的液体活检技术,优化新型纤维支气管镜技术及肺癌小样本取材技术是提高肺癌早期诊断率的重要手段。 Lung cancer is the leading contributor to morbidity and mortality from cancer worldwide, with its 5-year overall survival being only about 15.60%. Due to the lack of specific early screening methods for lung cancer, about 750%patients are diagnosed late. Therefore, it remains the big challenge for the early diagnosis of lung cancer. We need to pay more attention to the screening of lung cancer, and more precise assessment and management to the pulmonary nodules screened out. Further study on liquid biopsy, optimization of new fiberoptic bronchoscopy and the sampling methods to harvest small volume of lung tissue, could be helpful to improve the early diagnosis of lung cancer.
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2017年第3期331-335,共5页 Journal of Sichuan University(Medical Sciences)
基金 国家自然科学基金面上项目(No.81372504) 四川省科技厅项目(No.2016CZYD0001)资助
关键词 肺癌 早期诊断 Lung cancer Early diagnosis
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