期刊文献+

玻璃酸钠滴眼液治疗白内障超声乳化术后干眼症的临床疗效分析 被引量:21

Analysis on clinical effect of hyaluronic acid sodium eye drops in the treatment of xerophthalmia caused by cataract ultrasonic emulsification operation
在线阅读 下载PDF
导出
摘要 目的观察玻璃酸钠治疗白内障超声乳化术后干眼症的临床疗效。方法 120例(120眼)白内障超声乳化术后干眼症患者,随机分为治疗组和对照组,每组60例(60只眼)。对照组患者给予地塞米松眼膏和普拉洛芬滴眼液等常规治疗,治疗组患者在常规治疗的基础上加用玻璃酸钠滴眼液。比较两组术眼症状、泪液分泌试验、泪膜破裂时间、角膜荧光素染色水平。结果治疗组中痊愈20例,显效25例,有效13例,无效2例,总有效率为96.67%;对照组痊愈4例,显效8例,有效32例,无效16例,总有效率为73.33%;治疗组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论玻璃酸钠滴眼液治疗白内障超声乳化术后干眼症,可显著改善患者的主观症状,效果明显,可作为治疗干眼症有效药物之一。 Objective To observe clinical effect of hyaluronic acid sodium eye drops in the treatment of xerophthalmia caused by cataract ultrasonic emulsification operation. Methods A total of 120 patients(120 eyes) with xerophthalmia caused by cataract ultrasonic emulsification operation were randomly divided into treatment group and control group, with 60 cases(60 eyes) in each group. The control group received conventional therapy such as eexamethasone eye ointment and pranoprofen eye drops, and the treatment group received hyaluronic acid sodium eye drops on the basis of conventional therapy. Comparison were made on operative eye symptom, tear secretion test, breakup time of tear film and level of corneal fluorescein staining. Results The treatment group had 20 cured cases, 25 excellent cases, 13 effective cases and 2 ineffective cases, with total effective rate as 96.67%; the control group had 4 cured cases, 8 excellent cases, 32 effective cases and 16 ineffective cases, with total effective rate as 73.33%. The treatment group had higher total effective rate than the control group, and the difference had statistical significance(P〈0.05). Conclusion Hyaluronic acid sodium eye drops shows clear effect in the treatment of xerophthalmia caused by cataract ultrasonic emulsification operation, which can significantly improve subjective symptoms of patients. This method can be taken as an effective drug for the treatment of xerophthalmia.
作者 李晓达
出处 《中国现代药物应用》 2017年第1期141-143,共3页 Chinese Journal of Modern Drug Application
关键词 玻璃酸钠滴眼液 白内障超声乳化术 干眼症 Hyaluronic acid sodium eye drops Cataract ultrasonic emulsification operation Xerophthalmia
  • 相关文献

参考文献13

二级参考文献98

  • 1宋颖,周绍荣,张琳.干眼的诊治及其在眼科手术中的影响[J].国外医学(眼科学分册),2004,28(3):157-161. 被引量:16
  • 2李小燕,孙洁,曹永葆,潘松杨.白内障手术前后的泪膜破裂时间观察[J].临床眼科杂志,2006,14(1):49-50. 被引量:22
  • 3张汉承 周祖濂.泪膜的生理和病理.泪腺病学[M].北京:金盾出版社,1992.91.
  • 4陆博,张劲松.人工泪液对年龄相关性白内障术后患者泪膜的影响[J].国际眼科杂志,2007,7(4):1006-1008. 被引量:18
  • 5Bradley JC, Bradley RH, McCartney DL, et al. Serum growth factor analysis in dry eye syndrome[J].Clin Experiment Ophthalmol, 2008, 36(8) : 717-720.
  • 6Meloni M, De Servi B, Marasco D, et al. Molecular mechanism of ocular surface damage: application to an in vitro dry eye model on human corneal epithelium[J].Mol Vis,2011,17: 113-126.
  • 7Bekibele CO, Baiyeroju AM, Ajaiyeoba A, et al. Case control study of dry eye and related ocular surface abnormalities in Ibadan, Nigeria[J]. Int Ophthalmol, 2010,30(1): 7-13.
  • 8Johnson ME, Murphy PJ, Boulton M. Carbomer and sodium hyaluronate eyedrops for moderate dry eye treatment[J].Optom Vis Sci, 2008,85(8): 750-757.
  • 9王文玲.白内障术后干眼的原因分析及处理[J].临床眼科杂志,2007,15(5):456-457. 被引量:21
  • 10Ong - Tone L, Bell A. Practice patterns of Canadian Oph- thalmological Society members in cataract surgery - 2012 sur- vey[J]. Can J Ophthalmol, 2013, 48(2): 77.

共引文献463

同被引文献125

引证文献21

二级引证文献140

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部