摘要
禽流感(avian influenza AI)是由A型流感病毒引起的一种高度接触性传染病。H9N2是A型流感病毒的1个亚型,其谱系复杂,流行范围广,已经成为我国AI的主要亚型。尽管我国自1998年就开始进行H9N2亚型禽流感病毒(AIV)的防疫,但目前其疫苗株与流行株的抗原性已经出现了较大的差异。带毒野禽的迁徙不仅使H9N2AIV防控难度加大,而且使AI的流行不断复杂化;活禽交易市场为AIV重排以及跨种传播提供了有利的条件。此外,H9N2AIV感染谱在不断扩大,不仅感染哺乳动物,甚至已经感染了人群;因此,有必要重新认识H9N2AIV的兽医学和公共卫生学意义。现就H9N2AIV近年在我国的流行情况及其疫苗的研究进展作一综述。
Avian influenza is a highly contagious disease caused by influenza A virus （AIV）. Because of complex lineages and wide prevalence, H9N2 AIV has become major subtypes of avian influenza in China. Although the immunization measures have been taken in China since 1998 ,there are relatively large differences between the vaccine strains and pandemic strains in antigenicity at present. The migration of infected wild birds makes the prevention of HgN2 AIV much more difficult and the epidemic of avian influenza much more complicate. The live bird markets have contributed to the reassortment and the cross-species transmission of AIV. In addition, the host spectrum of H9N2 AIV is expanding. It infects not only mammal,but also human being. Therefore,it is necessary to re-recognize the significance of H9N2 AIV both in veterinary and public health. This article reviewed the research progress on prevalence and vaccines of HgN2 AIV in China in recent years.
出处
《中国兽医学报》
CAS
CSCD
北大核心
2017年第2期386-392,共7页
Chinese Journal of Veterinary Science
基金
国家自然科学基金面上资助项目(31372463)
吉林省教育厅"十二五"科学技术研究资助项目(吉教科合字[2015]第495号)
作者简介
丛彦龙（1977-），男，教授，博士。
通讯作者，E—mail：dingzhuang@jlu．edu．cn
