摘要
目的:比较隔日温和灸与中药调治亚健康状态的临床疗效差异。方法:选取亚健康受试者72例,采用随机数字表法分为温和灸组(36例)和药物组(36例)。温和灸组采用艾条温和灸干预,穴取关元、足三里、三阴交,隔日1次;药物组给予玉屏风颗粒口服,每日3次,均连续治疗2个月。治疗前后分别观察免疫球蛋白IgA、IgM、IgG与超氧化物歧化酶(SOD)、疲劳量表(FS-14)总积分和甲襞微循环变化。结果:与治疗前相比,两组患者免疫学指标、FS-14总积分及甲襞微循环各项积分在治疗后均有改善,差异有统计学意义(P<0.05,P<0.01);治疗后两组间比较,温和灸组血清IgM、IgG及SOD水平有高于药物组的趋势,但差异无统计学意义(均P>0.05);温和灸组FS-14总积分均值低于药物组(P<0.05);温和灸组治疗后甲襞微循环血液流态积分、袢周积分、总积分较药物组降低更明显(P<0.01,P<0.05)。结论:艾条隔日温和灸可显著改善亚健康受试者的疲劳状态、免疫功能与微循环障碍,明显优于中药玉屏风颗粒治疗。
Objective To compare the difference in the clinical therapeutic effects of the regulation of subhealthy condition between the mild moxibustion on alternate days and Chinese herbal medicine.Methods Seventytwo participants of subhealthy condition were assigned into a mild moxibustion group（36cases）and a medication group（36cases）according to random number table.In the mild moxibustion group,the intervention of mild moxibustion with moxa stick was applied to Guanyuan（CV 4）,Zusanli（ST 36）and Sanyinjiao（SP 6）,once every other day.In the medication group,yupingfenggranules were prescribed for oral administration,three times a day.The treatment was continued for 2months.Before and after treatment,the levels of IgA,IgM and IgG,SOD（superoxide dismutase）,the total score of fatigue scale 14（FS-14）and the score of nailfold microcirculation were observed separately.Results Compared with the results before treatment,the immune indices,the total score of FS-14 and the scores of nailfold microcirculation were all improved after treatment in the two groups,indicating the significant differences（P〈0.05,P〈0.01）.In comparison between the two groups after treatment,the levels of immune globulin,e.g.IgM,IgG and SOD in the mild moxibustion group were higher in tendency than those in the medication group,but without significant differences（all P〉0.05）.The total score of FS-14 after treatment in the mild moxibustion group was lower than that in the medication group（P〈0.05）.After treatment,in the mild moxibustion group,for the nailfold microcirculation,the flow state score,the periloop score and the total score were all reduced more apparently as compared with those in the medication group（P〈0.01,P〈0.05）.Conclusion Mild moxibustion with moxa stick on alternate days apparently relieves fatigue state,immune dysfunction and microcirculatory impairment in the subhealthy group.The results are apparently superior to the treatment with yupingfenggranules.
作者
何璐
王春华
胡玲
郝峰
吴子建
蔡荣林
王洁
HE Lu WANG Chunhua HU Ling HAO Feng WU Zijian CAI Ronglin WANG Jie(Clinical School of Acupuncture and Osteology, Anhui University of CM, Hefei 230038, China Institute of Acupuncture and Meridian, Anhui Academy of Chinese Medical Sciences Anhui Institute of International Business the Second Clinical Medical School, Nanjing University of CM)
出处
《中国针灸》
CAS
CSCD
北大核心
2017年第2期115-119,共5页
Chinese Acupuncture & Moxibustion
基金
国家重点基础研究发展计划(973计划)项目:2009CB 522905
安徽省科技攻关项目:1301042218
安徽省高校科研创新平台建设项目:2015TD033
关键词
亚健康状态
温和灸
免疫球蛋白
甲襞微循环
subhealthy state
mild moxibustion
immune globulin
nailfold microcirculation
作者简介
通信作者：胡玲（1956-），女，教授。研究方向：腧穴主治规律及作用机制研究。E-mail：hulingtcm@126．com
