摘要
目的观察布地奈德雾化吸入治疗老年哮喘的临床功效及对血清炎性因子的影响。方法选取我院2013年11月至2015年9月期间诊治的60例老年哮喘病患者作为本研究的对象,按照随机数表法分为观察组和对照组,每组各30例。对照组采用祛痰止咳和抗感染等常规治疗,观察组则在常规治疗基础上,加用布地奈德雾化吸入治疗。结果治疗后,观察组患者的IL-6、IL-8、IL-17等各血清炎性因子水平显著高于对照组(P<0.05);观察组治疗的总有效率为93.33%,显著高于对照组的60.00%(P<0.05)。结论采用常规治疗配合布地奈德雾化吸入的诊治方案能显著降低患者的IL-6、IL-8、IL-17等各血清炎性因子水平,减轻患者痛苦,提高治疗有效率,值得临床推广应用。
Objective To observe the clinical efficacy of budesonide inhalation in the treatment of senile asthma and effect on seruminflammatory factors. Methods 60 cases of patients with senile asthma admitted to our hospital from November 2013 to September 2015were selected as research subjects. All patients were randomly divided into observation group and control group, with 30 cases in each group.The control group received antitussive, expectorant and anti infective therapy, while the observation group received budesonide inhalationtherapy on the basis of conventional treatment. Results After treatment, the levels of serum inflammatory factors （IL-6, IL-8, IL-17） ofobservation group were significantly higher than those of control group （P〈0.05）. The total effective rate of observation group was 93.33%,significantly higher than 60.00% of the control group （P〈0.05）. Conclusions Conventional treatment combined with nebulized budesonideinhalation can significantly lower the levels of serum inflammatory factors （IL-6, IL-8, IL-17）, reduce the pain of patients and improve theeffective rate of treatment, which is worthy of clinical application.
出处
《临床医学工程》
2016年第9期1197-1198,共2页
Clinical Medicine & Engineering
关键词
布地奈德雾化
老年哮喘
血清炎性因子
临床疗效
Nebulized budesonide
Senile asthma
Serum inflammatory factors
Clinical curative effect
作者简介
李碧芳（1982-），女，广东韶关人，本科学历，主治医师，从事内科临床工作。
