摘要
目的研究延胡索Corydalis yanhusuo块茎的化学成分。方法运用常压硅胶柱色谱分离等现代分离手段,对延胡索块茎生物碱成分进行分离,结合理化性质和核磁共振波谱数据鉴定化合物结构。结果从延胡索块茎乙醇提取物中分得3个化合物,分别鉴定为1-[2-(N-甲基铵乙基)]-3,4,6,7-四甲氧基菲(1)、1-乙胺甲基-3,4,6,7-四甲氧基菲(2)、氧代海罂粟达林碱(3)。结论化合物1为新天然产物,化合物2为新化合物,命名为延胡索菲碱A;化合物3为首次从延胡索中分离得到。
Objective To study the chemical constituents from the rhizome of Corydalis yanhusuo. Methods The alkaloids were isolated and purified by silica column and other modem separation methods. The compounds were identified by nuclear magnetic resonance analysis. Results Three compounds were isolated and identified as 1-[2-（N-methylaminoethy）]-3,4,6,7-tetramethoxy- phenanthrene （1）, 1-（N-ethylaminomethy）-3,4,6,7-tetramethoxyphenanthrene （2）, and oxoglaucidaline （3）, respectively. Conclusion Compound I is a new natural product, compound 2 is a new compound named coryphenanthrine A, and compound 3 is isolated from this plant for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2016年第12期2084-2088,共5页
Chinese Traditional and Herbal Drugs
基金
江苏省高校优势学科建设工程资助项目(DE63063683)
作者简介
陈东东E—mail：chen—miller@qq．com
通信作者 陈建伟Tel：（025）85811280 E-mail：chenjw695@126．com
