期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

抗苗勒氏管激素评估卵巢储备功能的临床应用现状 被引量：33

Clinical status of anti-Müllerian hormone(AMH) in the evaluation of ovarian reserve function
原文传递
导出
摘要 卵巢储备功能指卵巢内存留卵泡的数量和质量,其能间接地反映女性的生育能力。抗苗勒氏管激素(anti-Müllerian hormone,AMH)作为卵巢特异性的生长因子,由颗粒细胞分泌,是预测卵巢储备功能的一个有效指标。血清AMH的水平可以预测卵泡池的大小、卵巢的反应性及女性的绝经年龄,同时可以评估癌症患者的卵巢储备功能。但AMH的测定值受到多种因素的影响,存在一定的局限性。 Ovarian reserve refers to the quantity and quality of remaining follicles in ovaries, which can indirectly reflect the fertility of the female. Anti-Miallerian hormone （AMH） as the ovary-specific growth factor secreted by granulosa ceils, is currently an effective indicator for predicting ovarian reserve function. The serum AMH level can predict the size of the follicle pool, ovarian response and the menopause age, but also can evaluate the ovarian function in patients with cancer. But the measurement of AMH level is influenced by many factors, thus the application of AMH still has some limitations.
作者 高姗 赵冬妮 谭季春
机构地区 中国医科大学附属盛京医院辅助生殖中心
出处 《生殖与避孕》 CAS CSCD 北大核心 2016年第8期648-652,共5页 Reproduction and Contraception
关键词 抗苗勒氏管激素(AMH) 卵巢储备 生育能力 局限性 anti-Mtillerian hormone （AMH） ovarian reseve fertility limitation
分类号 R714.8 [医药卫生—妇产科学]
作者简介 通讯作者：谭季春：Tel：＋86．18940251868；E-mail：tjczjh@163．com
  • 相关文献

参考文献34

  • 1Ji J, Liu Y, Tong XH, et al. The optimum number of oocytes in IVF treatment: an analysis of 2 455 cycles in China. Hum Reprod, 2013, 28(10):2728-34.
  • 2Jeppesen JV, Anderson RA, Kelsey TW, et al. Which follicles make the most anti-Miillerian hormone in humans? Evidence for an abrupt decline in AMH production at the time of follicle selection. Mol Hum Reprod, 2013, 19 (8):519-27.
  • 3Kelsey TW, Phoebe W, Nelson SM, et al. A validated model of serum anti-MiUerian hormone from conception to menopause. PLoS One, 2011, 6(7):395-402.
  • 4Schmidt L, Sobotka T, Bentzen JG, et al. Demographic and medical consequences of the postponement of parenthood. Hum Reprod Update, 2012, 18(1):29-43.
  • 5Rosen MP, Johnstone E, Mcculloch CE, et al. A characterization of the relationship of ovarian reserve markers with age. Fertil Steril, 2012, 97(1):238-43.
  • 6Tehrani FR, Mansournia MA, Solaymani-Dodaran M, et al. Age-specific serum anti-MOllerian hormone levels: estimates from a large population-based sample. Climacteric, 2014, 17(5):591-7.
  • 7Tehrani FR, Shakeri N, Solaymani-Dodamn M, et al. Predicting age at menopause from serum antimiillerian hormone concentration. Menopause, 2011, 18(7):766-70.
  • 8Delleman M, Faddy M J, Van D J, et al. The relationship between anti-Mallerian hormone in women receiving fertility assessments and age at menopause in subfertile women: evidence from large population studies. J Clin Endocrinol Metab, 2013, 98(5): 1946-53.
  • 9Delleman M, Depmann M, Eijkemans MJC, et al. Anti- Miillerian hormone is a more accurate predictor of indi- vidual time to menopause than mother's age at menopause. Hum Reprod, 2014, 29(3):584-91.
  • 10Committee El, Committee MFM, Liu K, et al. Advanced reproductive age and fertility. J Obstet Gyuaecol Can, 2011, 33(11):1165-75.

二级参考文献17

  • 1赵晓明,毛宇红,刘芳荪,孙赟,洪燕,林其德.卵巢储备功能测定在体外受精(IVF)技术中的临床价值探讨[J].生殖与避孕,2005,25(8):465-468. 被引量：13
  • 2Long WQ, Ranchin V, Pautier P, et al. Detection of minimal levels of serum anti-miillerian hormone during follow-up of patients with ovarian granulosa cell tumor by means of a highly sensitive enzyme-linked immunosorbent assay. J Clin Endocrinol Metab, 2000, 85(2):540-4.
  • 3Seifer DB, MacLaughlin DT, Christian BP, et al. Early follicular serum miillerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles. Fertil Steril, 2002, 77(3): 468-71.
  • 4Kansal Kalra S, Ratcliffe S, Gracia CR, et al. Randomized controlled pilot trial of luteal phase recombinant FSH stimulation in poor responders. Reprod Biomed Online, 2008, 17 (6):745-50.
  • 5Golan A, Ron-EI R, Herman A, et al. OHSS: an update review. Obstet Gynecol Surv,1989, 44(6):430-40.
  • 6Deffieux X, Antoine JM. Inhibins, activins and anti Mullerian hormone: structure, signalling pathways, roles and predictive value in reproductive medicine. Gynecol Obstet Fertil, 2003, 31(11):900-11.
  • 7Rajpert-DeMeyts E, Jorgensen N, Graem N, et al. Expression of anti-Mtillerian hormone during normal and pathological gonadal development association with differentiation of Sertoli and granulose cells. J Clin Endocrinol Metah, 1999, 84 (10):3836-44.
  • 8Baarends WM, Uilenbroek JT, Kramer P. Anti-mullerian hormone and anti-mullerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development,the estrous cycle, and gonadotropin-induced follicle growth. Endocrinology, 1995, 136(10):4951-62.
  • 9Hazout A, Bouchard P, Seifer DB, et al. Serum antimullerian inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiol. Fertil Steril, 2004, 82(5): 1323-9.
  • 10Gnoth C, Schuring AN, Friol K, et al. Relevance of anti-Mullerian hormone measurement in a routine IVF program. Hum Reprod, 2008, 23(6): 1359-65.

共引文献35

同被引文献243

引证文献33

二级引证文献240

生殖与避孕
2016年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
关于我们 | 版权声明 | 联系我们 | 帮助中心| 意见反馈
主办单位：上海市教育委员会
技术支持：重庆维普资讯有限公司
渝公网安备 50019002500403号
使用帮助 返回顶部