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透过慢性心力衰竭探讨宗气与心肌线粒体的关系 被引量:12

Relationship between pectoral qi and myocardial mitochondria in patients with chronic heart failure
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摘要 宗气灌注于心而"助心行血",宗气不足、功能失调为心力衰竭之根本;心肌线粒体参与能量代谢为心肌供能,其病理改变是现代医学中心力衰竭发生与发展的一个根本因素。通过对比两者的功能及它们在慢性心力衰竭中病理作用,发现二者均为慢性心力衰竭的一个本质性因素,在慢性心力衰竭过程中扮演相似角色;同时中医在治疗时应用的补宗气的补气药均在不同程度上对心肌线粒体有保护作用。但考虑宗气之功能较心肌线粒体的功能更为广泛,因此线粒体的生理功能或为宗气生理功能的一部分。 Zong Qi can help heart to run blood, and the disorder of Zong Qi is the fundamental of chronic heart failure in the theory of traditional Chinese medicine. Myocardium mitochondria provide energy to myocardium, and the disorder of it is essential to chronic heart failure in the modern medical theory. By comparing the roles that Zong Qi and myocardium mitochondria plays in the development process of chronic heart failure and the TCM treatment for CHF, the author found that Zong Qi as well as myocardial mitochondria exists a same pathogenesis pattern and Qi-invigorating herbs for Zong Qi could also prevent myocardial mitochondria. The fundamental of Zong Qi is wilder than it of myocardial mitochondria. So the conclusion is that maybe the function of myocardial mitochondria is a part corresponding matter to Zong Qi's function.
作者 姜文睿 王阶
出处 《中华中医药杂志》 CAS CSCD 北大核心 2017年第5期2084-2086,共3页 China Journal of Traditional Chinese Medicine and Pharmacy
关键词 慢性心力衰竭 宗气 心肌线粒体 补气药 Chronic heart failure Zong Qi Myocardial mitochondria Qi-invigorating herbs
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