摘要
目的:探究与分析阿司匹林联合三七皂苷治疗脑梗死的临床效果。方法:选取2010年10月-2015年6月本院神经内科收治的脑梗死患者180例,按照随机数字表法分为两组。治疗组患者90例,给予阿司匹林+三七皂苷进行治疗,对照组患者90例,仅给予阿司匹林进行治疗,对比两组患者的临床疗效及神经功能改变。结果:治疗后对照组与治疗组较治疗前神经功能缺损评分均明显降低,其中治疗组较对照组改善更显著,差异有统计学意义(P<0.05)。治疗组总有效率为81.11%,对照组为52.22%,治疗明显高于对照组,差异有统计学意义(P<0.05)。治疗后对照组与治疗组较治疗前MBI评分均明显提高,治疗组较对照组改善更显著,差异有统计学意义(P<0.05)。治疗前两组血清NSE、S100B、MBP、UFAP及H-FABP比较,差异均无统计学意义(P>0.05),治疗后治疗组与对照组较治疗血清NSE、S100B、MBP、UFAP及H-FABP水平均明显降低,治疗组较对照组改善更显著,差异均有统计学意义(P<0.05)。结论:阿司匹林联合三七皂苷治疗脑梗死疗效显著,可有效改善神经功能,值得推广。
Objective： To explore and analyze the clinical effect of Aspirin combined with Saponins of Panax Notoginseng in treating cerebral infarction.Method： From October 2010 to June 2015 180 cases of cerebral infarction treated in our hospital were selected.All patients were divided into two groups according to the random number table, the treatment group and the control group, 90 cases in each group.The patients in the treatment group were treated with Aspirin combined with Saponins of Panax Notoginsen.The patients in the control group were treated with Aspirin.The clinical efficacy and neurological function of two groups were compared.Result： The scores of neurological function impairment of two groups after treatment were significantly reduced compared with those before treatment （ P〈0.05 ） . Compared with the control group after treatment, the treatment group was more significant than that of the control group, there was statistical significance （P〈0.05） .The total effective rate of the treatment group was 81.11%, the control group was 52.22%, the total effective rate of the treatment group was significantly higher than that of the control group, there was statistical significance （ P〈0.05 ） .MBI score of two groups after treatment were significantly improved compared with those before treatment （P〈0.05） .Compared with the control group after treatment, the treatment group was more significant than that of the control group, there was statistical significance （ P〈0.05 ） . The serum levels of H-FABP, S100B, UFAP, MBP and NSE before treatment in two groups were not significantly different （ P〉0.05 ） .The serum levels of H-FABP, S100B, UFAP, MBP and NSE of two groups after treatment were significantly reduced compared with those before treatment （ P〈0.05 ） .Compared with the control group after treatment, the treatment group was more significant than that of the control group, there was statistical significance （ P〈0.05 ） .Conclusion： The combination of Aspirin combined with Saponins of Panax Notoginseng in the treatment of cerebral infarction is effective, which can change the nerve function effectively, it is worthy of promotion.
出处
《中国医学创新》
CAS
2016年第12期13-16,共4页
Medical Innovation of China
关键词
阿司匹林
三七皂苷
脑梗死
临床疗效
神经功能改变
Aspirin
Saponins of Panax Notoginseng
Cerebral infarction
Clinical effect
Neurological function
作者简介
通信作者：柯绪林
