摘要
目的:观察附子逍遥散配合快速针刺法治疗抑郁症的临床疗效及安全性。方法:将80例抑郁症患者按随机数字表法分为观察组和对照组,各40例。对照组患者给予帕罗西汀20 mg,qd;观察组患者给予附子逍遥散,水煎成200 ml,每日分3次服用,配合快速针刺法治疗。两组患者均6 d为1个疗程,共治疗6个疗程。观察两组患者临床疗效、治疗前后汉密尔顿抑郁量表(HAMD)评分、血清5-羟色胺(5-HT)含量和Asberg副作用量表(SERS)评分。结果:观察组患者有效率为82.5%,显著高于对照组患者的62.5%,差异有统计学意义(P<0.05);治疗后两组患者的HAMD评分均较治疗前显著下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组患者血清5-HT含量治疗后均有显著升高,与治疗前比较差异均有统计学意义(P<0.05),但组间比较差异无统计学意义(P>0.05)。治疗后观察组患者SERS评分均显著低于对照组,差异有统计学意义(P<0.05)。结论:附子逍遥散配合快速针刺法治疗抑郁症患者疗效显著,且安全性较好。
OBJECTIVE：To observe the clinical efficacy and safety of Fuzi xiaoyao powder combined with rapid acupuncture in the treatment of depression. METHODS：A total of 80 depression patients were randomly divided into observation group and control group,with 40 cases in each group. Control group was treated with paroxetine 20 mg,qd;observation group was given Fuzi xiaoyao powder 200 ml,one dose a day,at third,combined with rapid acupuncture. Two groups of patients for 6 days for a course of treatment,a total of 6 courses of treatment. Clinical efficacy,HAMD,serum content of 5-HT and Asberg side reaction scale（SERS）were observed in 2 groups. RESULTS：The effective rate of observation group was 82.5%,which was significantly higher than 62.5% of control group,with statistical significance（P〈0.05）;after treatment,HAMD of 2 groups decreased significantly,and the observation group was lower than the control group,with statistical significance（P〈0.05）. Compared with before treatment,erum content of 5-HT increased significantly in 2 groups after treatment,with statistical significance（P〈0.05）;there was no statistical significance between 2 groups（P〉0.05）. After treatment,SERS of observation group was significantly lower than that of control group,with statistical significance（P〈0.05）. CONCLUSIONS：Fuzhi xiaoyao powder combined with rapid acupuncture show certain therapeutic efficacy in the treatment of depression,with good safety
出处
《中国药房》
CAS
北大核心
2016年第11期1515-1517,共3页
China Pharmacy
基金
贵州省科学技术基金项目(No.黔科合J字[2013]2068号)
关键词
附子逍遥散
快速针刺法
抑郁症
Fuzhi xiaoyao powder
Rapid acupuncture
Depression
作者简介
副教授，硕士。研究方向：中药与针灸的临床应用。电话：0851-5609789。E—mail：wxq20080904@126．com
