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脓毒症休克的早期目标液体管理的研究进展 被引量:11

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摘要 脓毒症及脓毒症休克在重症患者中仍是常见并发症。尽管人们致力于改善脓毒症预后,但脓毒症死亡率仍然很高。Rivers等人提出早期目标导向治疗(early goal directed therapy,EGDT)可改善脓毒症预后,然而随着EGDT的推广,人们提出了越来越多的质疑,如改善预后方面、不良反应出现及复苏指标在指导液体复苏的可靠性等。本研究对这些质疑通过研究提出改进的方法做一综述。 Severe sepsis and septic shock are common complications of patients with critical illness. Despite efforts to improve its prognosis,its mortality still high. Rivers first reported that early goal-directed therapy (EGDT) significantly reduced the mortality rate of patients with severe sepsis and septic shock presenting to the emergency. However, as the EGDT promotion, there is increasingly doubt of EGDT. For example, improve the prognosis, its side effect and reliability of some goal.
出处 《当代医学》 2016年第11期11-13,共3页 Contemporary Medicine
关键词 脓毒症 脓毒症休克 早期目标导向性治疗 液体管理 Sepsis Sepsis shock Early goal-directed therapy Fluid management
作者简介 通讯作者:周立新,E-mail:drzhoulixin@gmail.com
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  • 1邱海波.应强化和落实严重感染的早期加强治疗策略[J].中华急诊医学杂志,2007,16(2):119-120. 被引量:22
  • 2成人严重感染与感染性休克血流动力学监测与支持指南[J].中华内科杂志,2007,46(4):344-349. 被引量:91
  • 3Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology ofsevere sepsis in the United States: Analysis of incidence, outcome,and associated costs of care[J]. Crit Care Med, 2001, 29: 1303-10.
  • 4Dellinger RP. Cardiovascular management of septic shock[J]. CritCare Med, 2003, 31: 946-55.
  • 5Martin GS, Mannino DM, Eaton S, et al. The epidemiology ofsepsis in the United States from 1979 through 2000[J]. N Engl JMed, 2003, 348: 1546-54.
  • 6Linde-Zwirble WT, Angus DC. Severe sepsis epidemiology:Sampling, selection, and society[J]. Crit Care, 2004, 8: 222-6.
  • 7Dombrovskiy VY, Martin AA, Sunderram J, et al. Rapid increase inhospitalization and mortality rates for severe sepsis in the UnitedStates: A trend analysis from 1993 to 2003[J]. Crit Care Med, 2007,35: 1414-5.
  • 8Phillip Dellinger, Mitchell M, Levy, et a1. Surviving SepsisCampaign Campaign:International Guidelines for Management ofSevere Sepsis and Septic Shock. Crit Care Med, 2013, 41: 580-637.
  • 9ProCESS Investigators. A randomized trial of protocol-based carefor early septic shock[J]. N Engl J Med, 2014, 370(18): 1683-93.
  • 10Osman D, Ridel C, Ray P, et a1. Cardiac filling pressures are notappropriate to predict hemodynamic response to volume challenge[J]. Crit Care Med, 2007, 35: 64-8.

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