摘要
目的：探讨医护一体化护理对食管癌患者术后不良情绪及免疫功能的影响。方法选择2012年10月—2013年10月符合入组条件的102例食管癌患者随机分为研究组（ n=52）和对照组（ n=50）研究组采用医护一体化护理干预,对照组采用常规护理。采用焦虑自评量表（ SAS）和抑郁自评量表（ SDS）评价两组患者手术前后的焦虑和抑郁状态,分别于术前、术后第1天及术后第8天检测两组患者免疫球蛋白（ IgA、IgG、IgM）、外周血淋巴细胞总数（ LYM）和细胞因子等免疫指标含量。结果手术前两组患者均存在焦虑、抑郁状态；手术后研究组患者焦虑、抑郁评分分别为（34.6±6.7）分、（33.7±6.9）分,均低于对照组,差异有统计学意义（P〈0.05）。术后第8天时,研究组患者IgA、IgM值,均较术后第1天回升,组内比较差异有统计学意义（t值分别为5.174,9.439；P〈0.05）；研究组患者血LYM和细胞因子CD4/CD8指标值,均高于对照组,组间比较差异有统计学意义（P〈0.05）,两组均高于术后第1天水平。结论医护一体化护理干预可以改善食管癌患者焦虑和抑郁不良情绪,增强患者的免疫功能,利于患者康复。
Objective To explore the influences of integrated nursing care on bad emotion and immune function of postoperative patients with esophageal cancer. Methods A total of 102 postoperative patients selected from October 2012 to October 2013 were randomly divided into research group （ 52 cases, integrated nursing care） and control group（50 cases, routine nursing）. Self rating anxiety scale （SAS） and self rating depression scale （ SDS） were used to evaluate the anxiety and depression of patients before and after operations. We detected the contents of immune index such as immunoglobulin （ IgA, IgG, IgM ） , peripheral blood lymphocyte count （ LYM ） , cytokine and etc. before operation, the first and eighth days after operation. Results Patients in the research and the control group all had anxiety and depression symptoms before operation. After operation, the scores of SAS （34. 6 ± 6. 7） and SDS （33. 7 ± 6. 9） of patients in the research group were lower than that in the control group （P〈0. 05）. Eighth days after operation, the contents of IgA and IgM rose again compared with that in the first postoperative day （t=5. 174,9. 439;P〈0. 05）. The contents of LYM and cytokine CD4/CD8 of patients in the research group were higher than that in the control group （ P〈0. 05）, and all of them were higher than that in the first postoperative day. Conclusions Integrated nursing care can relieve anxiety and depression of patients with esophageal cancer, enhance patients′immune function, and benefit patients′recovery.
出处
《中华现代护理杂志》
2015年第36期4378-4381,共4页
Chinese Journal of Modern Nursing
基金
国家自然科学基金面上项目（81072259）
关键词
食管肿瘤
焦虑
抑郁
免疫功能
医护一体化护理
Esophageal neoplasms
Anxiety
Depression
Immune function
Integrated nursing care
作者简介
通信作者：尤振兵，Email：jshayzb@126．com
