摘要
目的：优选出健脾温胃胶囊剂的最佳提取工艺。方法：以处方中党参炔苷的含量和浸膏收率作为优选评价指标,采用正交试验设计法优选健脾温胃胶囊剂的提取工艺条件。结果：最佳提取工艺条件为加8倍量的水,回流提取3次,每次1 h;采用低压真空浓缩干燥法（温度60℃,真空度在0.07~0.08MPa）对提取液进行浓缩、干燥。结论：最佳提取工艺条件提取效率高,稳定性和重复性好,可作为健脾温胃胶囊剂的提取工艺。
Objective： To optimizate the best extraction process of Jianpiwenwai the content of Lobetyolin and the extract yield as the evaluation index in the prescription of the optimum conditions of the extraction process, and the orthogonal test design as the optimized extraction conditions of Jianpi- wenwai Capsules. Results： The optimum extraction conditions were as follows： added 8 times amount of water and extracted 3 times for one hour every time. Low pressure vacuum concentration and drying method （the temperature was 60℃, and the vacuum degree was between 0. 07 -0. 08 MPa） was taken to condense and dry of the extract concentration. Conclusion： The optimum extraction conditions has high extraction efficiency, good stability and repeatability. It can be used as the extraction process of Jianpiwenwai capsules.
出处
《贵阳中医学院学报》
2016年第2期25-28,共4页
Journal of Guiyang University of Chinese Medicine
基金
贵州省科学技术厅贵阳中医学院科学技术联合基金课题,项目编号:黔科合中药字[2011]LKZ7025号
贵州省教育厅普通高等学校中药民族药(苗药)新剂型新制剂工程研究中心课题,项目编号:黔教合KY字[2014]22号
贵州省科技厅中药民族药炮制与制剂工程技术研究中心课题,项目编号:黔科合重G字[2012]4001号
关键词
正交设计
健脾温胃胶囊剂
提取工艺
党参炔苷
Orthogonal design
Jianpiwenwai Capsule
Extraction process
Lobetyolin
作者简介
冯果（1977-），男，中药学硕士，副教授，主要研究方向：中药新制剂新技术、中药药代动力学研究。
