摘要
目的:探究神经妥乐平对带状疱疹后遗神经痛(PHN)患者疼痛、抑郁评分的影响。方法:以2012年2月-2015年2月本院收治的80名PHN患者为研究对象,随机分为A、B两组。A组患者作为对照组,采用加巴喷丁及甲钴胺进行治疗,B组患者在A组的基础上给予神经妥乐平治疗,15d为一个疗程,记录并分析治疗开始(T0)、1周(T1)、半个月(T2)及1个月(T3)时患者的疼痛评分(VAS)、抑郁自评量表(SDS)。结果:T0阶段,两组间VAS、SDS均无显著差异(P>0.05);随着治疗的进行,两组患者在T1-3时VAS、SDS均较T0时显著下降(P<0.05);B组在T1-3VAS、SDS均显著低于同时间段的A组(P<0.05)。结论:神经妥乐平对PHN患者的疼痛治疗效果显著,改善患者抑郁情绪,提高患者生活质量。
Objective: To investigate the impact of neurotropin on pain, depression scores of patients with postherpetic neuralgia (PHN). Methods: From May, 2014 to Feb, 2015, 80 patients with PHN admitted in our hospital were randomly divided into group A(eontrol) and group B(gabap- entin and mecobalamin). The visual analogue scale (VAS) and self-rating depression scale (SDS) were measured and analyzed at pre-treatment (T0), a week after treatment(T1 ), half a month af- ter treatrnent(Tz) and a month after treatment(T3). Results: There was no significant difference of VAS and SDS between two groups at To (P〉0.05). As time went on, the scores of VAS and SDS in both groups significantly decreased when compared with To (P〈0.05). At T1-3, group B showed significant lower scores of VAS and SDS than those of group A (P(0.05). Conclusion: Neurotropin can significantly alleviate the pain and depression of patients with PHN and improve the quality of life.
出处
《武汉大学学报(医学版)》
CAS
2016年第2期293-295,共3页
Medical Journal of Wuhan University
作者简介
郑小平,女,1981,医学硕士生,主治医师,主要从事神经病理性疼痛研究
通讯作者:夏中元,男,1966-,教授,博士生导师,主要从事急危重症医学研究