摘要
目的 探讨重组人促卵泡激素联合人工受精治疗多囊卵巢综合征不孕患者的临床疗效。方法 选取自2014年1月-2015年4月在我院进行治疗的96例多囊卵巢综合征不孕患者进行研究分析,根据患者选择治疗方法 的不同分为观察组和对照组。采用重组人促卵泡激素联合人工受精进行治疗的56例患者为观察组,采用口服克罗米芬进行治疗的40例患者为对照组。治疗后对两组患者的体检指标、内分泌水平、卵泡相关指标及受精情况进行对比分析。结果 观察组患者的各项体检指标明显优于对照组,差异有统计学意义（P〈0.05）;观察组患者的LH、FSH、LH/FSH、T水平明显低于对照组,差异有统计学意义（P〈0.05）;观察组患者的卵巢体积及窦卵泡个数均少于对照组;而观察组优势卵泡的个数明显多于对照组,差异有统计学意义（P〈0.05）;观察组患者的受精情况明显优于对照组,差异有统计学意义（P〈0.05）。结论 采用重组人促卵泡激素联合人工受精治疗对PCOS不孕症进行治疗的疗效及安全性好,值得推广使用。
Objective To analyze the clinical effect of recombinant human follicle stimulating hormone combined with artificial insemination in the treatment of patients with polycystic ovary syndrome.Methods From January 2014 to April 2015,96 cases of patients with polycystic ovary syndrome treated in our hospital were analyzed,according to the different treatment methods of patients with different points of observation group and control group.Using recombinant human growth follicle stimulating hormone combined with artificial insemination treatment of 56 cases of patients as the observation group,the oral clomiphene in treatment of 40 cases of patients as the control group.After treatment,the two groups of patients with physical examination index,endocrine level,ovarian follicle related indicators and fertilization were compared and analyzed.Results The physical examination index of the observation group was better than the control group,the difference was statistically significant（P〈0.05）;The FSH,LH/FSH,T and LH levels in the observation group were significantly lower than those in the control group（P〈0.05）;The number of ovarian volume and the number of the dominant follicles in the observation group was significantly less than that in the control group,the difference was statistically significant（P〈0.05）.While the number of dominant follicles in the observation group was significandy more than that in the control group,the difference was statistically significant（P〈0.05）;the observation group in fertilization condition was significantly better than the control group,the difference was statistically significant（P〈0.05）.Conclusion Recombinant human follicle-stimulating hormone combined with IVF treatment for infertility PCOS have high efficacy and safety,and should be introduced.
出处
《中国现代医生》
2015年第36期96-99,共4页
China Modern Doctor
基金
江西省九江市科技计划项目(201402010)
关键词
重组人促卵泡激素
人工受精
PCOS
不孕症
高胰岛素血症
卵巢体积
Recombinant human follicle stimulating hormone
Artificial insemination
PCOS
Infertility
Hyperinsulinemia
Ovarian volume
