摘要
目的分析参附注射液治疗脓毒血症的效果及影响因素,为进一步提高参附注射液的临床应用提供参考依据。方法选取2011年1月至2014年1月我院ICU治疗的168例脓毒血症患者,以治疗过程中全程加用参附注射液的患者为病例组(82例),以未加用者为对照组(86例)。收集患者临床资料,应用Logistic回归分析参附注射液治疗脓毒血症的效果及影响因素。结果治疗7 d内病例组好转45例,迁延22例,死亡15例;对照组好转35例,迁延25例,死亡26例。两组比较差异有统计学意义(χ2=8.299,P=0.004)。Logistic回归分析病例组的治疗效果优于对照组(OR=2.557);患者APACHEⅡ评分、SIRS评分及C-反应蛋白(CRP)对疗效有影响。结论参附注射液对脓毒血症患者有较好的治疗效果。
Objective To investigate the effects and influence factors of shenfu injection in the treatment of serious sepsis by multivariate Logistic regression,so as to provide reference for clinical application. Methods 168 pa-tients with serious sepsis from January 2011 to January 2014 were retrospectively analyzed. Case group （ n=82 ） was defined as the administration of shenfu injection on the basis of Western medicine integrated treatment process,and con-trol group （n=86） was given Western medicine integrated treatment. Clinical data were reviewed and the potential in-fluence factors were analyzed by Logistic regression. Results 45 cases were improved,22 cases progressed and 15 ca-ses died in case group while 35 cases were improved,25 cases progressed and 26 cases died in control group after 7 d （χ2 =8. 299,P=0.004）. Logistic regression analysis showed that therapeutic effects in case group was superior to con-trol group （ OR = 2. 557 ） and APACHE Ⅱ scores, CRP and SIRS scores would influence the therapeutic effects. Conclusion Shenfu injection has a better effect on serious sepsis.
出处
《实用药物与临床》
CAS
2015年第9期1055-1057,共3页
Practical Pharmacy and Clinical Remedies
关键词
参附注射液
脓毒血症
治疗效果
Shenfu injection
Serious sepsis
Therapeutic effect
作者简介
通信作者
