摘要
目的探讨宫颈环形电切术(loop electrosurgical excision procedure,LEEP)联合重组人干扰素α-2b栓治疗宫颈上皮内瘤样病变的临床效果。方法选择2011年2月至2012年5月于本院妇科门诊就诊的宫颈上皮内瘤样病变患者100例为研究对象,随机分为观察组与对照组,每组各50例,两组患者均行LEEP治疗,观察组患者术后加用重组人干扰素α-2b栓治疗,比较两组患者临床疗效、创面愈合时间及术后并发症发生情况。结果观察组患者治愈率显著高于对照组(P<0.01),术后创面愈合时间显著短于对照组(P<0.01),术后并发症发生率低于对照组(P<0.05)。结论 LEEP联合重组人干扰素α-2b栓治疗宫颈上皮内瘤样病变效果显著,能够有效促进创面愈合,降低术后并发症发生率,值得临床推广应用。
Objective To investigate the clinical effect of loop electrosurgical excision procedure（LEEP） combined with recombinant human interferon α-2b suppository in the treatment of cervical intraepithelial neoplasia（CIN）. Method 100 patients with CIN in our hospital from February 2011 to May 2012 were selected and randomly divided into control group and observation group, 50 cases in each group, all patients taken LEEP to treat CIN, and recombinant human interferon α-2b suppository were taken in observation group in addition after operation. The clinical efficacy, wound healing time and postoperative complications were compared between the two groups. Result The cure rate in observation group was significantly higher than control group（P〈0.01）; postoperative wound healing time in observation group was significantly shorter than control group（P〈0.01）, postoperative complications was lower than control group（P〈0.05）. Conclusion LEEP combined with recombinant human interferon α-2b suppository in the treatment of CIN has obviously effect, can effectively promote wound healing, reduce postoperative complications, worthy of clinical application.
出处
《中国医学前沿杂志（电子版）》
2015年第7期46-48,共3页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
宫颈环形电切术
重组人干扰素Α-2B栓
宫颈上皮内瘤样病变
Loop electrosurgical excision procedure
Recombinant human interferon α-2b suppository
Cervical intraepithelial neoplasia
作者简介
通讯作者：陈丽霞E—mail：28595047@qq．com
