摘要
目的 观察参麦注射液对维持血透患者合并心功能不全的疗效。方法 选取2010年6月~2014年3月在本院血液透析治疗、出现心功能不全的62例维持血透患者,随机分为两组。A组29例采用血管紧张素转换酶抑制剂、促红细胞素、铁剂、叶酸等药物常规治疗;B组33例在常规治疗基础上,血液透析治疗过程中加用静脉滴注参麦注射液治疗。经4周治疗后,观察两组患者的心脏功能改善情况,检测血清脑钠肽情况。结果 经4周治疗后,B组的心功能改善情况优于A组,B组的脑钠肽水平较A组降低更明显,差异均有统计学意义（P〈0.05）。结论 参麦注射液治疗维持血液透析患者合并心功能不全疗效确切。
Objective To observe the curative effect of Shenmai Injection in the treatment of cardiac insufficiency of patients with maintaining hemodialysis. Methods 62 patients who received hemodialysis and suffered from cardiac insufficiency from June 2010 and March 2014 in our hospital were randomly allocated into Group A with 29 patients and Group B with 33 patients. Group A was treated with conventional drugs including angiotensin-converting enzyme inhibitors, erythropoietin, iron, and folic acid etc., Group B was further treated with intravenous Shenmai injection during hemodialysis. After 4 weeks of treatment, improvements of cardiac function of two groups were compared, and B-type natriuretic peptide was examined. Results After 4 weeks of treatment, the improvement of cardiac function of Group B was better than that of Group A, and the decrease in B-type natriuretlc peptide level of Group B was more significant than that of Group A. The differences were statistically significant（P 〈 0.05）. Conclusion The curative effect of Shenmai Injection in the treatment of cardiac insufficiency of patients with maintaining hemodialysis is effective.
出处
《中国医药科学》
2015年第13期73-75,共3页
China Medicine And Pharmacy
关键词
参麦注射液
血液透析
心功能不全
脑钠肽
Shenmai injection
Hemodialysis
Cardiac insufficiency
Natriuretic peptide
