摘要
随着百草枯(PQ)的广泛应用,PQ中毒事件数量逐年增加,已成为我国第二位的农药中毒事件。PQ对人有剧毒,中毒后致多脏器严重损害,病死率极高,其中毒机制尚不完全明确,氧自由基产生学说为大多数学者认可。PQ中毒暂无特效解毒药,临床上主要采取综合治疗的办法,如洗胃、导泻、吸附体内毒素、应用激素及免疫抑制剂、清除氧自由基、保护各脏器功能等,同时结合有效的血液净化手段,本文旨在对相关进展做一简要综述。
With paraquat （PQ） is widely used, the number of PQ poisoning is increasing year by year, it becomes second pesticide poisoning in China. PQ is highly toxic to people. After poisoning, it makes severe multiorgan damaged and high mortality rate. The poisoning mechanism of PQ poisoning is not entirely clear, while the oxygen free radicals theory is recognized by all most scholars. PQ poisoning has no specific antidote, and patients take a comprehensive approach to treat it, such as gastric lavage, catharsis, adsorbating toxins, use of eorticosteroids and immunosuppressive agents, eliminating oxygen free radicals, protecting the organ functions, and combining with effective blood purification methods. This paper aimed to make a briefly reviewe of the related developments.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第11期159-163,共5页
Chinese Journal of Clinicians(Electronic Edition)
关键词
百草枯
中毒
研究进展
Paraquat
Poisoning
Related developments
作者简介
通讯作者：黄教文，Email-charfie345295365@126．com
