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降钙素原、血清淀粉样蛋白及超敏C-反应蛋白水平检验在诊断早期脓毒血症的临床价值 被引量:4

Calcitonin Elements, Serum Amyloid Protein and High-sensitivity Creactive Protein Level Test in the Clinical Diagnosis of Early Sepsis
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摘要 目的探析降钙素原、血清淀粉样蛋白及超敏C-反应蛋白水平检验在早期脓毒血症临床诊断中的应用价值。方法选择该院2010年1月—2014年8月期间所收治的96例脓毒血症患者进行研究,根据是否为细菌感染分为A、B两组,所有患者均于清晨采集2 m L外周静脉血后测定PCT、hs-CRP、SAA水平,比较两组PCT、hs-CRP、SAA水平及三种检测方法敏感性、特异性。结果 A、B两组PCT、hs-CRP、SAA水平均存在较大差异(<0.05),差异有统计学意义。A、B两组中PCT检测敏感性均最高,与hs-CRP、SAA的两两比较均存在显著差异(<0.05),差异有统计学意义。结论与hs-CRP、SAA相比,早期脓毒血症患者的血清PCT水平检测具有更高敏感性与特异性,更利于脓毒血症早期确诊,进而提供治疗指导,临床价值较高,值得借鉴与应用。 Objective To probe into the elements of calcitonin, serum amyloid protein and high-sensitivity C-reactive protein level test in the early clinical diagnosis of sepsis. Methods 96 cases of sepsis patients treated in our hospital from January 2010-August 2014, according to whether the bacterial infection were divided into A, B two groups, determination of PCT, hs-CRP, SAA levels in all patients were collected 2ml in peripheral venous blood in the morning, compared two groups of PCT, hs-CRP, SAA levels and three sensitivity and specificity for detecting method. Results PCT, hs-CRP and SAA levels between Group A, B were significantly different ( 〈0.05), comparison was statistical significance. PCT detection sensitivity in group A and B was highest, compared to hs-CRP, SAA, differences were significant ( 〈0.05), there was statistical significance in comparison. Conclusion Compared with hs-CRP, SAA has higher sensitivity and specificity of the early detection of serum PCT levels in patients with sepsis, more conducive to sepsis early diagnosis, provide treatment guidelines, clinical value is high, is worthy of reference and application.
作者 赵永良
出处 《中外医疗》 2015年第10期176-177,共2页 China & Foreign Medical Treatment
关键词 降钙素原 血清淀粉样蛋白 超敏C-反应蛋白 早期脓毒血症 Calcitonin elements Serum amyloid protein High sensitivity C-reactive protein Early sepsis
作者简介 赵永良(1973.6-),男,河南焉陵人,本科,主管检验师,研究方向:临床医学检验。
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