摘要
目的研究噻托溴铵在老年慢性阻塞性肺病(COPD)合并Ⅱ型呼吸衰竭治疗中的临床疗效。方法90例COPD合并Ⅱ型呼吸衰竭且需要行无创呼吸机辅助呼吸的老年患者随机分为3组,A组为对照组,B组加用噻托溴铵,C组加用呼吸兴奋剂,观察治疗前后的动脉血气分析,心率(HR),呼吸频率(RR)等指标。结果加用噻托溴铵后PaCO2、PaO2、pH、SaO2值及RR、HR均有明显改善,无创呼吸机通气时间减少。结论噻托溴铵对COPD合并Ⅱ型呼吸衰竭有明显疗效。
Objective To examine the clinical efficacy of tiotropium bromide in the treatment of chronic obstructive pulmonary disease（COPD）combined with typeⅡ respiratory failure in elderly patients.Methods A total of 90 elderly patients with COPD combined with typeⅡ respiratory failure who required non-invasive ventilator support were randomly divided into three groups：control group,tiotropium group,respiratory stimulant group.Arterial blood gas analysis,heart rate（HR）,respiratory rate（RR）and other indicators were observed before and after treatment.Results PaCO2,PaO2,pH,SaO2,RR and HR were significantly improved and the time on non-invasive ventilator decreased in tiotropium group.Conclusion Tiotropium bromide is effective in the treatment of COPD combined with typeⅡ respiratory failure in elderly patients.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2015年第2期223-225,共3页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
关键词
噻托溴铵
慢性阻塞性肺病
Ⅱ型呼吸衰竭
临床疗效
tiotropium bromide
chronic obstructive pulmonary disease
type Ⅱ respiratory failure
clinical effect
作者简介
朱珊，女，1981年生，主治医师，医学硕士，E-mail：zhuzhumao@126．com
通讯作者，Corresponding author，E-mail：drzhaosu@sina．com
