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多指标正交优选双龙颗粒水提工艺 被引量:2

Studies multi-indexes on water-extraction techniques of Sl particle by orthogonal design
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摘要 目的优选双龙颗粒的水提提取工艺。方法采用正交设计法,以提取干膏量,盐酸麻黄碱含量,苦杏仁苷含量为考察指标,对双龙颗粒水提部分的加水量、水煮时间、提取次数三因素进行优选研究。结果确定了合理可行的工艺条件,即加水量为20倍量(8、6、6),煎煮三次,每次1h。含量测定方法为HPLC法。结论优选的水提取工艺科学合理、稳定可行。 Objective To optimize water-extraction technology of Sl Particle. Methods The optimized extracting condition of Sl Particle were investigated by determining the dried extract,the content of ephedrine chloride and the content of amygdalin with orthogonal design method.Three factors,water volume,decocting time and extracting times,were considered to effect the extracting efficiency of active component. Results The reasonable extracting conditions were to decoct for three times with water for 1 hour each time, and the total water volume were 20 times corresponding to the herbal weight.The quantitative method of ephedrine chloride and amygdalin was used by HPLC method. Conclusion This optimized water-extraction technology was scientific,reasonable,stable and feasible.
出处 《中国医药科学》 2015年第3期48-50,56,共4页 China Medicine And Pharmacy
基金 北京高等学校青年英才计划项目(YETP1993)
关键词 正交设计 双龙颗粒 盐酸麻黄碱 苦杏仁苷 HPLC法 Orthogonal design Sl particle Ephedine chloride Amygdalin HPLC method
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