摘要
目的探讨复合凝乳酶胶囊治疗儿童功能性消化不良(FD)的临床疗效及其与幽门螺杆菌(Hp)感染的关系。方法 160例儿童Hp阳性FD患儿随机分为对照组及观察组各80例。对照组予以常规治疗,观察组应用复合凝乳酶胶囊治疗,比较两组的临床疗效。结果观察组的总有效率为100.00%,与对照组的97.50%无明显差异(P>0.05),但观察组的优良率达93.75%,显著高于对照组的76.25%(P<0.05);观察组的Hp根除率为91.25%,显著高于对照组的73.75%(P<0.05);观察组治疗后临床评分显著低于对照组(P<0.05),且Hp根除组显著低于未根除组(P<0.05);观察组的不良反应率和Hp复发率分别为5.00%、0.00%,显著低于对照组的28.75%和6.25%(P<0.05)。结论复合凝乳酶胶囊治疗儿童FD疗效显著,不良反应少,根除Hp有利于提高临床疗效。
Objective To investigate the clinical efficacy composite rennet capsules in treatment of functional dyspepsia（FD） and its relationship with Helicobacter pylori（Hp）. Methods 160 children with Hp positive FD were randomly divided into digital control group and observation group, 80 cases in each. The control group received conventional treatment, observation group received complex rennet capsule treatment, the clinical efficacy of two groups were compared. Results The total effective rate of observation group 100.00%, had no significant difference with 97.50% of the control group（P〉0.05）,but the excellent rate of observation group was 93.75%, significantly higher than the 76.25%（P〈0.05）; Hp eradication rate of observation group was 91.25%, significantly higher than the 73.75%（P〈0.05）; after treatment,the clinical score of observation group was significantly lower than the control group（P〈0.05）, and Hp eradication group was significantly lower than Hp non-eradication group（P〈0.05）; adverse reaction rate and HP relapse rate of observation group was 5.00% and 0.00, significantly lower than the 28.75% and 6.25% in the control group（P〈0.05）. Conclusion Composite rennet capsules in treatment of children with FD has significant effect, fewer adverse reactions, the eradication of Hp help improve clinical efficacy.
出处
《中国处方药》
2015年第3期107-108,共2页
Journal of China Prescription Drug
