摘要
目的探讨多囊卵巢综合征(PCOS)患者不同血清维生素D水平与来曲唑促排卵结局的关系。方法回顾性分析来曲唑促排卵治疗PCOS患者193例,根据血清25(OH)D水平,分为25(OH)D正常组(A组)、25(OH)D相对不足组(B组)、25(OH)D缺乏组(C组),分析血清中不同25(OH)D水平与来曲唑促排卵治疗后临床妊娠率的关系。结果 A组妊娠率为29.17%,B组为14.08%,C组为12.00%,A组显著高于B组和C组(P<0.05),而B组与C组临床妊娠率无显著差异(P>0.05)。结论维生素D低水平的PCOS患者促排卵后临床妊娠率较低,为此类患者补充维生素D可能提高其临床妊娠率。
Objective To explore the relations between different serum vitamin D levels and letrozole ovulation outcome of patients with polycystic ovary syndrome （ PCOS） .Methods A retrospective analysis was made in 193 patients with PCOS to receive letrozole ovulation treatment .They were divided into three groups according to the serum 25 （ OH ） D levels, i.e., normal group （ group A ） , relatively deficient group （ group B ） , and deficient group （ group C ） , so as to analyze the relations between different serum 25（OH） D levels and the clinical pregnancy rate after letrozole ovulation treatment .Results The pregnancy rate in group A, B, and C was 29.17%, 14.08%and 12.00%, respectively, and the pregnancy rate in group A was significantly higher than those in group B and C （P〈0.05）, while the clinical pregnancy rate had no significant difference between group B and C （P〉0.05）. Conclusion The clinical pregnancy rate of patients with PCOS and low level of serum vitamin D level is relatively low after ovulation induction and supplementary of vitamin D may increase their pregnancy rate .
出处
《西南国防医药》
CAS
2015年第3期242-244,共3页
Medical Journal of National Defending Forces in Southwest China
基金
河北省医学科学研究课题计划项目(20130239)
关键词
多囊卵巢综合征
妊娠
来曲唑
polycystic ovary syndrome
vitamin D
serum 25 （OH） D
pregnancy
letrozole
