摘要
目的探讨抗抑郁药SSRI引起干眼的病因以及眼表分析仪在人工泪液治疗干眼症状前后的应用价值。方法选取近年来患抑郁症的患者,根据其患病情况分成3类,用眼表分析仪进行眼部检查,然后给予抗抑郁药5-羟色胺再摄取抑制剂(SSRI)帕罗西丁(赛乐特)治疗,若变化明显则局部滴用人工泪液(聚乙烯醇滴眼液)并对治疗前后眼部情况进行分析,用眼表分析仪观察患者的眼表情况。结果抗抑郁药SSRI可引起患者局部干眼,用眼表分析仪观察患者的干眼症状明显加重。结论 SSRI引起患者干眼的症状病因探讨以及眼表分析仪在对于干眼症的诊断和研究中有重要意义。
Objective To investigate the causes of dry eye symptoms induced by antidepressants SSRI, and to e- valuate the role of ocular surface analyzer in the treatment of dry eye before and after artificial tear-shaped. Methods Re- cently diagnosed depression patients were divided into 3 groups and received eye examinations with the ocular surface analy- zer, and then were given 5-serotonin reuptake inhibitor （ SSRI ） Paroxetine （ PHT ）. Ocular surface analyzer was used to observe the tear film and ocular surface cendition. Tropical artificial tear （0.5% hydroxypropyl methyl cellulose） was pre- scribed if there were significant changes in tear film. Results SSRI can cause focal dry eyes. Significant worsening of the dry eye symptoms can be observed with the ocular surface analyzer. Conclusion The awareness of dry eye symptoms caused by SSRI antidepressants and the use of ocular surface analyzer for diagnosis and research has important clinical value
出处
《临床眼科杂志》
2015年第1期66-69,共4页
Journal of Clinical Ophthalmology
关键词
眼表分析仪
干眼
抗抑郁药
5-羟色胺再摄取抑制剂
赛乐特
Ocular surface analyzer
Dry eye
Antidepressant
5-semtonin reuptake inltibitors （SSRI）
Paroxetine
作者简介
通讯作者：杨燕宁（Email：ophyyn@163．com）
