摘要
目的 了解轻度胃肠炎伴发的良性婴儿惊厥 (BICE)在华北地区的发病概况。方法 自 1999年 1月至 2 0 0 1年 4月对因急性胃肠炎 (GE)合并无热惊厥的患儿进行临床观察和出院后随访。结果 在观察研究时间内共有 898例GE患儿住院 ,伴无热惊厥者 16例 ,其中男 9例 ,女 7例 ,发病年龄最小 4 5个月 ,最大 2 6个月 ,1～2岁者共 12例。临床GE症状不严重 ,伴无热惊厥呈全身强直阵挛样发作 ,发作间期EEG(12例 )和视频脑电图监测 (4例 )主要改变为 4～ 5Hzθ波活动和正常睡眠EEG背景波 ,无一例有棘 慢波或尖波发放。其它实验室检查包括 :血清电解质、血糖、肝功能检查均正常 ,3例做脑脊液检查、10例做头颅CT检查结果均正常。惊厥发作易控制。出院后随访 14例 (平均间隔 1年 2个月 )未见惊厥复发 ,生长发育如正常儿。结论 轻度GE可以伴有无热惊厥 ,其发生比例约为 1 78% (16/898) ,惊厥形式为全身强直 阵挛样发作 ,易于控制 ,预后良好 ,故可称之为BICE。
Objective To investigate the incidence of benign infantile convulsions(BICE)associated with mild gastroenteritis.Methods Infants with gastroenteritis (GE) accompanied with seizures were observed and followed up from January 1999 to April 2001.Results 16 out of 898 patients with CE, including 9 boys and 7 girls, aged 1～2 years old, showed afebrile seizures. The seizures was attacked as generalized tonic clonic pattern (GTCs), with an active 4～5Hz θ and normal sleep background waves on EEG. No spike or sharp wave was recorded. No significant change was found in serum electrolysis, blood sugar, liver function and CT scans during the attack.The seizures were easy to be controlled and no further attack was observed in 14 cases during the follow up period.Conclusions The incidence of afebril convulsion with mild gastroenteritis was about 1 78% in infants with CE. The seizure, with a GTCs pattern during the attack and a good prognosis in future, was termed as BICE.
出处
《中国实用儿科杂志》
CSCD
北大核心
2002年第4期216-218,共3页
Chinese Journal of Practical Pediatrics
