摘要
目的探究西医常规治疗联合大黄附子汤对脓毒症患者胃肠功能障碍的改善作用。方法选取河南大学第一附属医院2017年1月至2017年12月期间收治的脓毒症患者140例作为研究对象,依据治疗方法的不同分为试验组和对照组。对照组采用西医常规治疗,试验组采用西医常规联合大黄附子汤治疗,观察两组患者胃肠功能障碍改善效果。结果两组患者在治疗前及治疗后1d血浆D-乳酸水平比较差异无统计学意义(P>0.05);试验组治疗后7d及14d血浆D-乳酸水平均明显低于对照组(nmol/L:0.13±0.01vs.0.18±0.02,0.09±0.01vs.0.17±0.01,P均<0.05);治疗后,试验组胃肠功能障碍评分(分:1.53±0.26vs.1.13±0.28)与APACHEⅡ评分(分:11.26±2.67vs.8.54±2.58)改善情况均明显优于对照组(P<0.05)。结论在西医常规治疗的基础上给予大黄附子汤可通过调节患者体内血浆D-乳酸浓度达到改善胃肠功能的效果。
Objective To explore the effect of routine western medicine combined with Dahuang Fuzi decoction on gastrointestinal dysfunetion in sepsis patients.Methods 140 patients with sepsis admitted in bur hospital from January 2017 to December 2017 were divided into experimental group and control group aecording to the different treatment methods.The control group was treated with routine western medicine.The experimental group was treated with routine western medicine,combined with rhubarb aconite decoction,and the improvement effect of routine dysfunction was observed in both groups.Results There was no significant difference in plasma D -lactic acid levels between the two groups before treatment and 1 day after treatment (P >0.05 ),while that in control group was significantly lower than that in control group at 7 find 14 days after treatment (nmol/L:0.13±0.01 vs. 0.18 ±0.02,0.09 ±0.01 vs.0.17 ±0.01,P <0.05).The improvement of gastrointestinal dysfunetion seore(score:1.53 ±0.26 vs.1.13 ±0.28)and APACHE 11 score (score:11.26 ±2.67 vs.8.54 ±2.58)in the experimental group was significantly better than that in the control group (P,<0.05),the difference was statistically significant (P <0.05 ).Condusion In the course of treating sepsis patients,the main direction is to improve the gastrointestinal function of patients.On the basis of routine western medicine treatment,rhubarb aconite decoction can improve gastrointestinal function by regulating plasma.D -lactic acid concentration in patients.
作者
杨超
王玉珍
白奎
张二辉
高海波
Yang Chao;Wang Yu-zhen;Bai Kui;Zhang Er-hui;Gao Hai-bo(Intensive Care Unit, First Affiliated Hospital of Henan University, Zhengzhou 475000, China)
出处
《中国急救医学》
CAS
CSCD
北大核心
2019年第2期153-155,共3页
Chinese Journal of Critical Care Medicine
关键词
大黄附子汤
脓毒症
胃肠功能障碍
Rhubarb aconite decoction
Sepsis
Gastrointestinal dysfunction
作者简介
杨超(1969-),男,副主任医师,E-mail:nnmb0625@126.com。
