摘要
目的探讨中性粒细胞/淋巴细胞比值(NLR)诊断颅内动脉粥样硬化性狭窄(ICAS)的价值。方法动脉粥样硬化性缺血性脑卒中患者115例分为血管狭窄组(ICAS组,51例)和无血管狭窄组(NS组,64例),分析ICAS的独立影响因素,采用ROC曲线评价NLR对ICAS的预测价值。结果 ICAS组年龄、NLR和高血压比例均高于NS组(P<0.05)。高血压、高同型半胱氨酸血症和NLR是ICAS独立影响因素(P<0.05)。NLR预测ICAS的曲线下面积为0.660,最佳临界值为3.080,灵敏度为59.4%,特异度为72.5%。结论 NLR用于诊断ICAS具有临床应用价值。
Objective To explore the value of the ratio of neutrophil to lymphocyte(NLR)in diagnosing intracranial atherosclerotic stenosis(ICAS).Methods A total of 115 patients with atherosclerotic ischemic stroke was divided into two groups of non-vascular stenosis(group NS,64 cases)and ICAS(51 cases).The independent influencing factors of ICAS were analyzed and ROC curve was drawn to evaluate the predictive value of NLR in diagnosing ICAS.Results The age,NLR and hypertension proportion were higher in group ICAS than those in group NS(P<0.05).The hypertension,hyperhomocysteinemia and NLR were the independent factors for ICAS(P<0.05).Taking 3.080 as a cut-off value,the sensitivity and specificity were 59.4%and 72.5%for the NLR to predict ICAS.Conclusion NLR has clinical value in diagnosing the patients with ICAS.
作者
蔡志荣
徐宇浩
于明
CAI Zhirong;XU Yuhao;YU Ming(Department of Neurology,Affiliated Hospital,Jiangsu University, Zhenjiang 212001,CHINA)
出处
《江苏医药》
CAS
2018年第12期1386-1388,共3页
Jiangsu Medical Journal
基金
国家自然科学基金(81373512)
江苏省社会发展基金(BE2017699)
作者简介
通信作者:于明E-mail:yuming7251@163.com.
