摘要
为提高中药检测指标在中药检验中的合理性,使得检测指标在保障用药安全性和有效性方面发挥应有的作用,防止检测指标的形式化。选取阿魏酸这一检测指标讨论其在功效方面的针对性,对比药性、药味、归经、基原等方面的特异性。查阅《中华人民共和国药典》(简称《中国药典》)发现以阿魏酸作为检测指标的中药有3个,分属于活血化瘀药、补血药和解表药,阿魏酸既不能代表活血化瘀药的全部功效也无补血、解表作用。通过检索文献发现《中国药典》中含有阿魏酸的中药有30余种,对比其药性、药味、归经、基原等发现无特异性。阿魏酸作为多味中药质量评价指标的合理性值得商榷。
In order to improve the rationality of TCM detection index in TCM testing,make the detection index play its due role in guaranteeing the safety and effectiveness of drug use,and prevent the formalization of detection index.Ferulic:acid is selected as an example to discuss its specificity in efficacy,and to compare its specificity in medication,taste,meridian tropism and origin.Referring to the Chinese Pharmacopoeia,we found that there are three traditional Chinese medicines with ferulic acid as the detection index,which belong to blood-activating and stasis-removing drugs,blood-tonifying drugs and relieving superficial syndrome drugs.Ferulic acid can neither represent the full effect of blood-activating and stasis-removing drugs nor the effect of blood-reinforcing drugs,nor the effect of removing superficial syndrome.Through searching literature,more than 30 kinds of traditional Chinese medicines containing ferulic acid were found in the Chinese Pharmacopoeia,and no specificity was found by comparing their medicinal properties,taste,meridian tropism and origin.The rationality of ferulic acid as a quality evaluation index of multi flavor Chinese medicine is questionable.
作者
王卫明
彭慧
张贵君
WANG Wei-ming;PENG Hui;ZHANG Gui-jun(Zibo Wanjie Tumor Hospital,Zibo 255213,China;Zibo Wanjie Institute of Traditional Chinese Medicine,Zibo 255213,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2018年第12期5677-5679,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
药典
阿魏酸
质量标准
Pharmacopoeia
Ferulic acid
Quality standard
作者简介
通讯作者:张贵君,山东省淄博市博山区经济开发区健康大道1号淄博万杰中医药研究所,邮编:255213,电话:0533-4913666E-mail:guijunzhang@163.com.
