摘要
目的 研究0.2%阿法根(Brimonidine)滴眼液对视网膜血流的影响。方法 选取开角型青光眼或高眼压症患者 15例,采用自身对照方法,于0.2%阿法根滴眼液治疗前和治疗后 2h分别行海德堡视网膜血流计(HRF)检查,观察视网膜中央动脉颞上、颞下、鼻上、鼻下4条分支血管血容量、血流及血流速度的变化。结果 0.2%阿法根滴眼液治疗前后视网膜中央动脉颞上、颞下、鼻上、鼻下4条分支血管的血容量、血流及血流速度无明显改变。结论 0.2%阿法根滴眼液局部使用对视网膜血流无影响。
Objective To investigate the effect of Brimonidine 0. 2% on blood flow using the Heidelberg Retina Flowmeter (HRF). Methods using auto-control method,we examined the volume, flow and velocity of the superior nasal and temporal, the inferior nasal and temporal artery of retina before and after single instillation of Brimonidine 0. 2% for 2 h. Results There are no significant changes in volume, flow and velocity of four arteries after the administration of Brimonidine 0. 2%. Conclusion There are no significant ocular haemodynamic benefits associated with Brimonidine therapy.
出处
《眼科研究》
CSCD
北大核心
2001年第4期353-355,共3页
Chinese Ophthalmic Research