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0.2%阿法根滴眼液对视网膜血流影响的研究

Effect of Brimonidine 0.2% on retinal blood flow
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摘要 目的  研究0.2%阿法根(Brimonidine)滴眼液对视网膜血流的影响。方法 选取开角型青光眼或高眼压症患者 15例,采用自身对照方法,于0.2%阿法根滴眼液治疗前和治疗后 2h分别行海德堡视网膜血流计(HRF)检查,观察视网膜中央动脉颞上、颞下、鼻上、鼻下4条分支血管血容量、血流及血流速度的变化。结果 0.2%阿法根滴眼液治疗前后视网膜中央动脉颞上、颞下、鼻上、鼻下4条分支血管的血容量、血流及血流速度无明显改变。结论 0.2%阿法根滴眼液局部使用对视网膜血流无影响。 Objective To investigate the effect of Brimonidine 0. 2% on blood flow using the Heidelberg Retina Flowmeter (HRF). Methods using auto-control method,we examined the volume, flow and velocity of the superior nasal and temporal, the inferior nasal and temporal artery of retina before and after single instillation of Brimonidine 0. 2% for 2 h. Results There are no significant changes in volume, flow and velocity of four arteries after the administration of Brimonidine 0. 2%. Conclusion There are no significant ocular haemodynamic benefits associated with Brimonidine therapy.
出处 《眼科研究》 CSCD 北大核心 2001年第4期353-355,共3页 Chinese Ophthalmic Research
关键词 青光眼 药物治疗 视网膜血流 阿法根滴眼液 glaucoma therapy retinal blood flow
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参考文献6

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