摘要
细菌感染已成为全球性问题，且细菌耐药情况越来越严重，因此，我们需要寻找一种新的、不会使细菌产生耐药性的杀菌方法，这一探索应该属于高度优先的研究和开发项^[1]。
Blue light is commonly used to kill Propionibacterium acnes in clinic.Furthermore,blue light exhibits a good bactericidal effect against Helicobacter pylori,methicillin-resistant Staphylococcus aureus,Pseudomonas aeruginosa,and many oral bacteria in laboratory studies.The bactericidal mechanism of blue light as commonly accepted consists photo-excitation of intracellular porphyrins resulting in production of cytotoxic reactive oxygen species which can inactivate bacteria.Blue light can kill bacteria without additional exogenous photosensitizers.In addition,it produces little harm to mammalian cells.Therefore,as the increasing emergence of antibiotic resistant microorganisms,blue light might be a good antibacterial tool.
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2014年第3期258-261,共4页
Chinese Journal of Burns
关键词
光疗法
灭菌
治疗结果
卟啉类
Phototherapy
Sterilization
Treatment outcome
Porphyrins
作者简介
通信作者：姚敏，Email：my058@vip．sina，com，电话：18917797606
