摘要
目的:分析氯吡格雷合并辛伐他汀对急性冠脉综合症患者(ACS)血脂和高敏C反应蛋白(hs-CRP)的影响。方法:选取经临床诊断为ACS的患者130例,其中54例接受常规辛伐他汀治疗,76例接受辛伐他汀联合氯吡格雷治疗,分析治疗40 d后患者hs-CRP及血脂的变化。结果:两组患者治疗40 d后血脂及hs-CRP均下降,但联合用药组hs-CRP下降明显,两组血脂下降无显著差异。结论:氯吡格雷联合辛伐他汀能显著降低ACS患者血浆中hs-CRP水平,有利于对炎症的控制和抑制斑块生长。
Objective： To analysis the effects of clopidogrel combined with simvastatin on blood lipids and high sensitivity C-reactive protein（hs-CRP） in patients with acute coronary syndrome（ACS）. Methods： One hundred and thirty patients with ACS were divided into two groups： simvastatin group（54 patients） and simvastatin combined with clopidogrel group（76 patients）. The levels of blood lipids and hs-CRP were detected before and 40 days after treatment. Results： The hs-CRP and blood lipids levels of patients significantly decreased in two groups. Compared with simvastatin group, the hs-CRP levels significantly decreased, but the blood lipids levels had not significant decreased. Conclusion： Treatment with clopidogrel combination with simvastatin can decrease the blood hs-CRP. It suggest that it may inhibit inflammatory responses, increase atherosclerotic plaque stabilization in ACS patients.
出处
《中国医学装备》
2014年第6期108-110,共3页
China Medical Equipment
作者简介
石惠娟，女，（1962-），本科学历，副主任护师。成都军区昆明疗养院，从事心理康复、疗养护理工作。
