摘要
Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lobelanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applications have also indicated that L. chinensis possesses a number of pharmacological activities(e.g., diuretic, choleretic, breathing excitement, anti-venom, anti-bacterial, and anticancer). This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development of L. chinensis.
Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lo- belanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applica- tions have also indicated that L. chinensis possesses a number of pharmacological activities （e.g., diuretic, choleretic, breathing ex- citement, anti-venom, anti-bacterial, and anticancer）. This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development ofL. chinensis.
基金
supported by the Macao Science and Technology Development Fund(No.102/2012/A3)
the Research Fund of the University of Macao(No.MYRG 208(Y3-L4)-ICMS11-WYT)
作者简介
[Corresponding author] WANG Yi-Tao： Prof., Tel/Fax： 853-839746 91,853-28841358; E-mail： ytwang@umac.mo
