摘要
Pyriminostrobin, a new acaricide, was discovered in our previous studies. Because introducing fluorine into organic compounds can increase bioactivity, pyriminostrobin was modified as a series of strobilurin-pyrimidine derivatives for biological screening. The compounds were characterized by 1H NMR, MS and elemental analysis. Preliminary bioassays demonstrated that compounds 7e and 7i exhibited significant control against Tetranychus cinnabarinus （Boisd.） at 0.625 mg L^-1, and their acaricidal potencies were higher than pyriminostrobin in a greenhouse. The relationship between structure and acaricidal activity was also studied.
Pyriminostrobin, a new acaricide, was discovered in our previous studies. Because introducing fluorine into organic compounds can increase bioactivity, pyriminostrobin was modified as a series of strobilurin-pyrimidine derivatives for biological screening. The compounds were characterized by 1H NMR, MS and elemental analysis. Preliminary bioassays demonstrated that compounds 7e and 7i exhibited significant control against Tetranychus cinnabarinus （Boisd.） at 0.625 mg L^-1, and their acaricidal potencies were higher than pyriminostrobin in a greenhouse. The relationship between structure and acaricidal activity was also studied.
基金
the Outstanding Young Scholarship from the National Natural Science Foundation of China(No.30825043)
NSFC(No.21172202)
the Outstanding Scholar Foundation of Henan Province(No.094100510019)for financial support
supported by the National Key Basic Research Program of China(973 Program)(Nos.2010CB126105 and 2012CB724501)
the National Key Technology Support Program during the 12th Five-Year Plan Period(Nos.2011BAE06B00,2011BAE06B01,2011BAE06B02,2011BAE06B03 and 2011BAE06B05)
作者简介
Corresponding authors. E-mail addresses： liuchangling@sinochem.comCorresponding authors.E-mail addresses：changjunbiao@zzu.edu.cn
