摘要
目的探讨饮用农药污染水源与农村消化道恶性肿瘤高发的相关性。方法采用系统抽样方法抽取青田县5个乡镇2009--2011年75例消化道恶性肿瘤病例作为病例组，根据年龄性别匹配原则选取同期150例消化道疾病患者作为对照组，进行病例对照研究。根据取水点距离农药污染源的距离及人群暴露年限判定饮用水源危险度。结果病例组消化道恶性肿瘤以胃癌为主，占48．00％（36／75）。全县5个乡镇中，海溪乡饮用污染水源的人群比例较高，达80．00％（36／45）。病例组暴露于污染饮用水源的比例为41．33％（31／75），高于对照组的18．67％（28／150），差异有统计学意义（41-3％：18．7％，x2=13．28，P〈O．01）。人群饮用污染水源患消化道恶性肿瘤的可能性是不饮用污染水源人群的3．07倍（OR=3．07，95％CI：1．66-5．69）。结论长时间饮用受农药污染的农药污染水源可能是农村消化道恶性肿瘤高发的危险因素之一。
Objective To analyse correlation between water source polluted by pesticide and high incidence rate of digestive tract malignant tumor in countryside. Methods Seventy-five cases of digestive tract malignant tumor patients from 5 villages of Qingtian in 2009--2011 were selected by systematic sampling method as the cases group, 150 cases of digestive tract diseases were matched according to the age and sex as control group, and then carried out a case-control study. The risk degree of drinking water source was judged according to the distance of water intake point to pesticide pollution source and the exposure years. Results Gastric cancer was the main malignant tumor of digestive tract in case group, accounting for 48.00% （36/75）. In all 5 towns, Haixi village had the largest number of people （80.00%,36/45） who drank the pollution water. The rate of patients who drank pollution water in case group was higher than that in control group （41.33% ：18.67%,x2=13.28, P〈0.01）. The possibility of people who drank pollution water suffering from gastrointestinal cancer was 3.07 times higher than that of not drank pollution water （OR=3.07, 95%CI：1.66-5.69）. Conclusions Drinking pesticide pollution farmland water for long time maybe one of the risk factor for high incidence of malignant tumors.
出处
《国际流行病学传染病学杂志》
CAS
2013年第6期405-407,共3页
International Journal of Epidemiology and Infectious Disease
关键词
肿瘤
农药
水污染
消化道
Tumor
Pesticides
Water pollution
Digestive tract
