摘要
贵州省 1992～ 1999年共报告急性弛缓性麻痹 (AFP)病例 114 8例 ,采集AFP病例粪便标本 975例 ,分离出肠道病毒 2 87株 ,其中脊髓灰质炎 (脊灰 )病毒 (PV) 12 8株 ,非脊灰肠道病毒 (NPEV) 15 9株。 113株PV经中国预防医学科学院国家脊灰实验室鉴定 ,有 8株Ⅰ型野毒株 ,5株疫苗变异株 ,10 0株疫苗相关株。 1993年以前病毒分离以PVⅠ型野毒株为主 ,1994年以后已连续 6年未分离到PV野毒株。省卫生防疫站脊灰实验室监测工作水平显著提高 ,至 1997年各项相关技术指标中除合格粪便标本采集率外 ,其余均达到了世界卫生组织 (WHO)和卫生部的质量控制要求 ,1997年、1999年通过WHO的认证。但监测任务依然严峻和繁重 。
In 1992～1999,a total of 1,148 AFP cases were reported in Guizhou Province, and from them,975 stool specimens were collected 287 virus strains had been isolated out of 975 stool specimens with a virus isolation rate of 29 4%, 128 of the 287 strains were polioviruses (PV), the left 159 strains were non polio enteroviruses (NPEV) 113 strains of polioviruses were identified by the National Poliomyelitis Laboratory Among them,8 strains were wild type polio I (all of them were isolated in 1993), 5 strains were polio vaccine derived strains and the other 100 strains were vaccine strains The virus isolation was dominated by wild type polio I before 1993,and it has been 6 years long that we haven't found wild type poliovirus since 1994 The working level on aetiology surveillance of our provincial polio laboratory has been dramatically improved because of our's working hard for many years Up to 1997,all the laboratory indexes had reached the quality control requirement of WHO,except the rate of two adequate stool specimen collection within 14 days of AFP case, the laboratory was accredited by WHO in 1997 and in 1999 Although we have made great progress,some works still fall far short of the requirement of WHO in current,the AFP surveillance task is still rigorous and strenuous,we must make sustained efforts
出处
《中国计划免疫》
2000年第6期325-327,共3页
Chinese Journal of Vaccines and Immunization
