摘要
目的 分析2010年新疆地区维吾尔族、哈萨克族及汉族成年居民血脂异常的患病现状及分布特点.方法 2010年采用分层整群随机抽样方法,抽取年龄≥18岁的维吾尔族居民3625名,男性1773名,女性1852名,年龄为（42.89±15.95）岁；哈萨克族居民4148名,男性1649名,女性2499名,年龄为（44.14±13.27）岁；汉族居民3733名,男性1563名,女性2170名,年龄（49.66±12.24）岁,共调查了11 506名.进行问卷调查和身体检查,抽取空腹静脉血检测TG、TC、LDL-C和HDL-C.结果 维吾尔族调查对象TG、TC、HDL-C和LDL-C水平分别为（1.31±1.03）、（4.44±1.20）、（1.41±0.62）和（2.44±0.81） mmol/L；哈萨克族分别为（1.24 ±0.99）、（4.55±1.31）、（1.41±0.62）和（2.40±0.87） mmol/L；汉族分别为（1.62±1.34）、（4.60±1.10）、（1.16±0.68）和（2.23±0.93） mmol/L.维吾尔族、哈萨克族及汉族血脂异常患病率分别为：42.4％（1537/3625）、31.6％（1311/4148）、30.2％（1127/3733）,标化患病率分别为：42.4％、31.8％、28.2％,维吾尔族血脂异常患病率高于哈萨克族和汉族,差异有统计学意义（Х^2=179.87,P＜0.01）.维吾尔族、哈萨克族和汉族男性血脂异常的标化患病率分别为52.6％、35.4％、33.2％,维吾尔族男性高于哈萨克族和汉族男性,差异有统计学意义（Х^2=159.19,P＜0.01）.汉族、维吾尔族、哈萨克族高TG血症标化患病率分别为：9.3％,9.3％,17.3％,汉族高TG血症患病率高于维吾尔族及哈萨克族（Х^2=172.55,P＜0.01）.哈萨克族的TC异常标化率（6.9％）高于维吾尔族（5.2％）,差异有统计学意义（Х^2=10.20,P＜0.01）.维吾尔族、哈萨克族、汉族的低HDL-C血症标化患病率分别为：33.6％,20.8％,11.1％,维吾尔族高于哈萨克族和汉族（Х^2 =552.82,P＜0.01）,哈萨克族高于汉族（Х^2=138.01,P＜0.01）.3个民族间的高LDL-C血症差异均无统计学意义（P＞0.05）.结论 新疆地区3个民族血脂异常患病率均高于全国患病率,且存在民族、年龄及性别间差异.
Objective To investigate the prevalence of dyslipidemia among the Uyghur,Kazakh,and Han adults in Xinjiang Region and to analyze the features of distribution.Methods 3625 Uygur residents,1773 males and 1852 females,aged （42.89 ± 15.95） years old,4148 Kazakh residents,1649males and 2499 females,aged （44.14 ± 13.27） years old,and 3733 Han rtesidents,1563 males and 2170females,aged （49.66 ± 12.24） years old,were selected by stratified cluster random sampling method in year 2010,11 506 adults in total.Questionnaire and physical examination were conducted,including fasting venous blood samples to test the levels of triglyceride （TG）,total cholesterol （TC）,low density lipoprotein cholesterol （LDL-C）,and high density lipoprotein cholesterol （HDL-C）.Results The levels of TG,TC,HDL-Cand LDL-C were separately （1.31 ± 1.03）,（4.44± 1.20）,（1.41 ±0.62）,and （2.44±0.81） mmol/Lin the Uygur adults; separately （1.24±0.99）,（4.55 ± 1.31）,（1.41 ±0.62）,and （2.40 ± 0.87） mmol/L in the Kazakh adults; and （1.62 ± 1.34）,（4.60 ± 1.10）,（1.16 ± 0.68）,and （2.23 ± 0.93） mmol/L in the Han adults,respectively.The general prevalence of dyslipidemia in the Uygur,Kazakh,and Han adults were 42.4% （1537/3625）,31.6% （1311/4148）,and 30.2% （1127/3733） respectively; while the age-standardized prevalence were separately 42.4%,31.8%,and 28.2%.The prevalence of dyslipidemia in the Uygur adults was significantly higher than it of the Kazakh and Han adults,with statistical significance （Х^2 =179.87,P 〈 0.01）.The standardized prevalence of dyslipidemia in the Uygur males was 52.6%,significantly higher than it of the Kazakh and Han males （35.4% and 33.2%）,with statistical significance （Х^2 =159.19,P 〈 0.01）.The prevalence of hypertriglyeeridemia among the Han adults was 17.3%,which was significantly higher than it among the Uyghur and Kazakh adults （Х^2 =172.55,P 〈 0.01）.The prevalence of hypercholesterolemia in Kazakh （6.9%） was higher than it in Uygur （5.2%）,with statistical significance （Х^2 =10.20,P 〈 0.01）.The prevalence of low HDL-C hyperlipidemia in the above 3 ethnics were 33.6%,20.8% and 11.1%,respectively; while Uygur was the highest（Х^2 =552.82,P 〈 0.01）,followed by Kazakh,which was higher than Han（Х^2 =138.01,P 〈0.01）.There was no significant difference in the prevalence of high LDL-C hyperlipidemia among the adults of the 3 ethnics.Conclusion The prevalence of dyslipidemia among the Uygur,Kazakh,and Han adults in xinjiang were all higher than the national average prevalence,the distribution of dyslipidemia varied with ethnicity,age and sex.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2013年第10期949-953,共5页
Chinese Journal of Preventive Medicine
基金
国家科技支撑计划（2009BAI82B04）
新疆生产建设兵团国际科技合作项目（2009YD33）
作者简介
通信作者：郭淑霞，Email：pge888@sina．com
