摘要
目的探讨点定量弹性成像(ElastPQ)测量正常肝脏硬度中的影响因素。方法对293名正常人进行ElastPQ,获取肝脏硬度值,分析性别和年龄对肝脏硬度测量的影响。选取其中34名,分析不同肝段、呼吸时相、探头位置及操作者对肝脏硬度测量的影响。结果 S5的测值变异系数(CV)最小(19.94%),且与S1、S2、S3的硬度值差异有统计学意义(P均<0.05),而与S4、S6、S7及S8相比差异无统计学意义(P均>0.05);呼气末和吸气末肝脏硬度值分别为(4.14±0.93)kPa和(3.35±0.55)kPa(P<0.001);正常肝脏硬度值为(3.87±1.04)kPa,正常男性肝脏硬度值显著高于女性[(4.18±1.29)kPa vs(3.71±0.85)kPa,P=0.002];不同探头位置、操作者及年龄间的肝脏硬度值差异无统计学意义(P>0.05)。结论测量正常肝脏硬度时,应尽量于同一呼吸时相在右侧肋间隙选择S5进行;对于正常男性及女性,应分别制定不同的肝脏硬度参考值。
Objective To investigate the impact factors of normal liver stiffness measurement in elastography point quantification （ElastPQ）. Methods Totally 293 normal subjects underwent liver stiffness measurement （LSM） by using Elast- PQ, the liver stiffness values were recorded, and the impact of gender and age on liver stiffness were analyzed. The impact of different liver segments, respiratory phases, probe positions and examiners on LSM were evaluated in 34 subjects. Results S5 exhibited the lowest coefficient of variation （CV） on LSM （19.94 %）. Significant differences of liver stiffness value were found between S5 and S1, S2 and S3 （all P〈0.05）. There was no significant difference between S5 and S4, S6, S7 nor S8 （all P〉0.05）. The liver stiffness value at the end-expiration was significantly higher than that at the end-inspi- ration （[4.14_＋0.93]kPa vs E3.35-＋-0.55]kPa, P〈0. 001）. The normal liver stiffness value was （3.87＋_1.04）kPa, of men was significantly higher than that of women （[-4.18_＋1.29]kPa vs [3.71~0.85]kPa, P=0. 002）. There was no sig- nificant difference among different probe positions, examiners and ages （P〉0.05）. Conclusion LSM should be performed at the same breathing phase in S5 with inter-costal approach by ElastPQ for normal liver. The reference values of liver stiff- ness for the normal men and women need to be defined differently.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第11期1838-1841,共4页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金(81101060
81071163)
关键词
弹性成像技术
肝脏
硬度值
影响因素
Elasticity imaging techniques
Liver
Stiffness value
Influencing factor
作者简介
凌文武（1985-），男，安徽枞阳人，硕士，医师。研究方向：腹部超声诊断。E—mail：lingwenwubing@163．com
[通讯作者]罗燕，四川大学华西医院超声科，610041。Email：luoyan77@vip．sina．com
