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脉冲冲洗联合负压封闭引流处理创面疗效观察 被引量:4

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摘要 目的观察脉冲冲洗联合负压封闭引流处理创面的临床疗效。方法将51例四肢需行清创术的患者随机分为观察组27例和对照组24例,观察组采用脉冲冲洗联合负压封闭引流,对照组单纯采用负压封闭引流,观察两组1周后创面细菌清除率、创面需再次清创率,采用ELISA法检测两组创面肉芽组织中TNF-α、IL-6、MMP-9、TIMP-1水平。结果与对照组比较,观察组创面细菌清除率高,更换负压敷料率低,创面肉芽组织中TNF-α、IL-6、MMP-9、MMP-9/TIMP-1低(P均<0.05)。结论脉冲冲洗联合负压封闭引流处理创面疗效较好,且能够提高细菌的清除率,促进肉芽生长。
出处 《山东医药》 CAS 2013年第39期89-91,共3页 Shandong Medical Journal
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参考文献13

  • 1杨帆,白祥军.创面治疗的新理念——负压封闭引流技术[J].中华外科杂志,2010,48(5):387-389. 被引量:57
  • 2Witkowski W, Jawien A, Witkiewicz W, et al. Initial multi-centre observations upon the effect of a new topical negative pressure de- vice upon patient and clinician experience and the treatment of wounds[J]. Int Wound J, 2009,6(2) :167-174.
  • 3Schintler MV, Negative pressure therapy: theory and practice[ J]. Diabetes Metab Res Rev, 2012,28 (Suppl 1 ) :72-77.
  • 4Witkowski W, Jawien A, Witkiewicz W, et al. Initial multicentre observations upon the effect of a new topical negative pressure de- vice upon the effect of a new topical negative pressure device upon patient and clinician experience and the treatment of wounds [ J ]. Int Wound J, 2009,6(2) :167-174.
  • 5Ubbink DT, Westerbos SJ, Evans D, et al. Topical negative pres- sure for treating chronic wounds[ J]. Cochrane Database Syst Rev, 2008,16(3) : CD001898.
  • 6李丹,刘堃.改良封闭式负压引流联合局部间断高浓度氧疗治疗严重软组织损伤效果观察[J].山东医药,2012,52(6):86-87. 被引量:9
  • 7I-Iaimi S, Wahlman M, Mannila M, et al. Pulse-lavage washing is an effective method for defatting of morselized allograft bone in the operating theater [ J ]. Acta orthop, 2005,79 ( 1 ) :94-97.
  • 8Clarius M, Hauck C, Seeger JB, et al. Pulsed lavage reduces theincidence of radiolucent lines under the tibial tray of oxford uni- com. parmental knee arthroplasty:pulsed lavage versus syringe lay- age[ J]. Int orthop, 2009,33 (6) : 1585-1590.
  • 9Mote GA, Malay DS. Efficacy of power-pulsed lavage in lower ex- tremity wound infections a prospective observational study [ J ]. J Foot Ankle Surr. 2010.49 (2) : 135-142.
  • 10章莹,夏远军,吴文,谢会斌.一次性脉冲冲洗吸引器应用于创面清创的前瞻性随机对照研究[J].中华创伤骨科杂志,2011,13(7):631-634. 被引量:12

二级参考文献46

  • 1孔瑞群 ,邓卫芬 ,刘莲 ,李杰霞 .氧疗加TDP照射后用湿润烧伤膏治疗褥疮溃疡期的临床观察及护理[J].国际医药卫生导报,2005,11(2):117-118. 被引量:8
  • 2阿玛德,余国荣,陶圣祥,余黎,王显勋,彭飞.封闭式负压引流治疗下肢大面积软组织缺损的临床观察[J].医学新知,2005,15(2):45-46. 被引量:88
  • 3高少茹,林惠卿,郭少英,许雪华,陈银崧,刘春梅.渭良伤科油和红花酒精治疗老年卧床患者Ⅰ期压疮的对比研究[J].护理学报,2006,13(6):1-3. 被引量:19
  • 4Fleisehmann W, Strecker W, Bombelli M. Vacuum sealing as treatment of soft damage in open fractures. Unfallchirurg, 1993, 96:488-492.
  • 5Vig S. A systematic review of topical negative pressure therapy for acute and chronic wounds. Br J Surg,2008 ,95 :685-692.
  • 6Koehler C, Niederbichler AD, Jung F J, et al. Wound therapy using the vacuum-assisted closure device:clinical experience with novel indications. J Trauma,2008,65:722-731.
  • 7Witkowski W,Jawien A, Witkiewicz W, et al. Initial multi-centre observations upon the effect of a new Topical Negative Pressure device upon patient and clinician experience and the treatment of wounds. Int Wound J,2009,6 : 167-174.
  • 8Webb LX,Pape HC. Current thought regarding the mechanism of action of negative pressure wound therapy with reticulated open cell foam. J Orthop Trauma,2008,22 : 135-137.
  • 9Morykwas MJ, Argenta LC, Shelton-Brown El, et al. Vacuumassisted closure:a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg, 1997,38 : 553-562.
  • 10Duby T, Hofman J, Cameron D, et al. A randomized trial in the treatment of venous leg ulcer comparing short stretch bandages, four layer bandage system and long stretch paste bandage system. Wounds, 1993,5:276-279.

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