摘要
目的:观察雄激素对SD大鼠毛发生长及毛发周期的影响。方法:采用单因素及复合因素导致雄性大鼠肾虚脱发模型造模的方法,观察大鼠背部新生毛发生长情况,并通过血清中睾酮含量,HE染色切片来综合分析雄激素与脂质对毛发生长、毛囊形态、毛囊数量等的影响。结果:与空白对照组相比,模型组的毛发生长情况得到了明显抑制。结论:雄激素含量过高和高脂质饮食可导致类似肾虚型脱发。
Objective： To observe the influence of androgen on hair growth and hair cycle of SD rats.Methods： Use single and compound factors to make the hair loss of kidney-deficiency male rat.Observe and record the hair growth condition of the new on the rats＇ back.Analyze the influence among the growth,morphology and quantity of hair comprehensively which is caused by androgen and lipid,through HE sections and the testosterone content in blood serum.Results： To compare with the control group,the hair growths in model group are inhibited obviously.Conclusions： Over high-level androgen can give rise to the inhibition of the growth of hair follicle,and this can result in the establishment of the alopecia model in male rats of kidney-deficiency.
出处
《中医学报》
CAS
2013年第11期1669-1670,I0001,共3页
Acta Chinese Medicine
基金
浙江省卫生厅立项课题(编号:2009B117)
关键词
脱发模型
肾虚
大鼠
alopecia model
kidney-deficiency
rat
作者简介
李荣群（1974-），男，山东青岛人，医学博士，副教授，主要从事于中医药治疗风湿免疫病的研究和临床工作。
