摘要
采用高效液相色谱法测定丹参超微粉体和常规粉体中丹参酮IIA体外溶出量和溶出速率。丹参超微粉体和常规粉体中丹参酮I IA体外溶出量无显著性差异,超微粉体的溶出速率较常规粉体明显增加。实验表明超微粉碎可明显提高丹参酮IIA溶出速率。
HPLC techniques were used to detect the dissolution amount and the dissolution rate of Tanshinone IIA from ultra-micro and traditional powder of Radix et Rhizoma Salviae miltiorrhizae. There was not statistically significant difference between the two powder of Radix et Rhizorna Salviae miltiorrhizae in dissolution amount, Compared with traditional powder , the dissolution rate of ultra- micro powder of Radix et Rhizoma Salviae miltiorrhizae was increased obviously. The ultra-micro porphyrization could improve the dissolution rate of Tanshinone IIA.
出处
《光谱实验室》
CAS
2013年第5期2335-2338,共4页
Chinese Journal of Spectroscopy Laboratory
基金
新疆医科大学大学生创新性实验计划项目(CX2011039)
关键词
丹参
超微粉碎
溶出度
丹参酮ⅡA
Radix et Rhizoma Salviae miltiorrhizae
Super fine crushing
Dissolution
Tanshinone IIA
作者简介
张海英（1973-）,女,新疆省霍城县人,副主任,中药师,硕士,主要从事中药药理研究工作.
