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子宫内膜癌复发现状和影响因素调查研究 被引量:6

Research on recurrent situation and risk factors of endometrial cancer
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摘要 目的探讨子宫内膜癌复发现状,分析子宫内膜癌复发的危险因素。方法对1998年12月—2012年11月本科收治的100例子宫内膜癌患者的临床资料进行回顾性分析,按照复发情况分为复发组及未复发组,将2组患者一般资料、病理类型、手术病理分期、细胞学分型、肌层浸润深度、淋巴结转移的差异等数据进行汇总,进行单因素及多因素Logistic回归分析。结果复发组腹水细胞学分型、肌层浸润深度、病理分级和淋巴结转移的比例均显著高于未复发组。多因素Logistic回归分析显示,侵肌深度、病理分级和淋巴结转移与子宫内膜癌术后复发有着密切关系。结论肌层浸润深度、病理分级和淋巴结转移是子宫内膜癌患者术后复发的危险因素,对于合并复发危险因素的患者在术后应密切随访,选择合适的术后辅助治疗方案,减少复发,改善预后。 Objective To explore the recurrent condition of endometrial cancer and analyze its recurrent risk factors.Methods The clinical data of 100 patients with endometrial cancer treated in our hospital from December 1998 to November 2012 was retrospectively analyzed.According to the recurrent condition,the patients were randomly divided into recurrent group and non-recurrent group.The general data,pathological types,surgical pathological staging,cytological types,myometrial infiltration depth and lymphatic metastasis of two groups were summarized so as to make Logistic regression analysis on single and multiple factors.Results The proportions of ascetic cytological types,myometrial infiltration depth,pathological grades and lymphatic metastasis in recurrent group were significantly higher than those in non-recurrent group.Multiple-factor Logistic aggression analysis showed that postoperative recurrence of endometrial cancer was in close relation with the myometrial infiltration depth,pathological grades and lymphatic metastasis.Conclusion The myometrial infiltration depth,pathological grades and lymphatic metastasis are liable to induce the postoperative recurrence of endometrial cancer,so a close follow-up visit and appropriate postoperative complementary therapy should be given to patients with recurrent risk factors to reduce the recurrence and improve the prognosis.
出处 《实用临床医药杂志》 CAS 2013年第13期145-147,共3页 Journal of Clinical Medicine in Practice
基金 中国高校医学期刊临床专项资金(11320090)
关键词 子宫内膜癌 复发 影响因素 单因素分析 多因素分析 endometrial cancer recurrence risk factor single factor analysis multiple-factor analysis
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