摘要
子宫内膜癌患者在较早期时即出现了症状,所以多数可以通过内膜的活检得以诊断。根据本病的生物学行为和病理特点可以将其分为子宫内膜样癌和非子宫内膜样癌。手术治疗是首选的治疗手段。目前,对子宫内膜样癌患者主要采用全面的手术分期,术后根据病理的结果即有无高危因素决定是否给予辅助治疗;对非子宫内膜样癌的手术方式更倾向于类似卵巢癌的肿瘤细胞减灭术。放射治疗虽然可以明显减少手术后的局部复发,但却不能改善患者的生存。化疗主要用于特殊的病理类型、肿瘤组织分化差、晚期或复发的患者。大剂量孕激素对子宫内膜癌有肯定疗效。
Endometrial cancer is one of the most common gynecologic malignancies and can be diagnosed by D＆C as some symptoms appear in early stage for patients. It is also divided into endometroid and non - endometroid by biological behavior and pathologic characteristics. The surgical staging has been adopted by the International Federation of Gynecology and Obstetrics （FIGO） and widely used. Surgery is the first choice of therapy for endometrial cancer. A variety of surgical methods are selected for the different histological diseases. The comprehensive surgical staging should be performed for the patients with endometroid carcinoma, whether the adjuvant chemotherapy or radiotherapy should also be given depend upon the high - risk factors in pathologic results after the operation. For the patients with non- endometroid type, the surgical therapy should be taken similarly to cytoreductive surgery for ovarian cancer. Radiotherapy has been broadly utilized for the patients with endometrial cancer. Although the local recto＇fence rate was obviously decreased, any benefit for survival could not be found for the patients. Chemotherapy has usually been applied for some patients with high grade, advanced disease, recurrences and some special types like non- endometroid. Hormonal therapy, especially high dose progestational agents, can produce good antitumor responses.
出处
《癌症进展》
2006年第1期13-18,共6页
Oncology Progress
关键词
子宫内膜癌
治疗
endometrial cancer treatment
